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ON THE HYDRODYNAMIC ANALYSIS OF MACROMOLECULAR CONFORMATION

机译:宏观构型的水动力分析

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摘要

Hydrodynamics provides a powerful complementary role to the traditional ''high resolution'' techniques for the investigation of macromolecular conformation, especially in dilute solution, conditions which are generally inaccessible to other structural techniques. This paper describes the state of art of hydrodynamic representations for macromolecular conformation, in terms of (1) simple but straightforward ellipsoid of revolution modelling; (2) general triaxial ellipsoid modelling; (3) hydrodynamic bead modelling; (4) the ability, especially for polydisperse macromolecular systems, to distinguish between various conformation types; (5) analysis of macromolecular flexibility. [References: 182]
机译:流体力学为传统的“高分辨率”技术提供了强大的补充作用,用于研究大分子构象,尤其是在稀溶液中,这是其他结构技术通常无法达到的条件。本文从以下方面描述了大分子构型的流体动力学表示技术:(1)简单而直接的椭圆旋转模型; (2)一般的三轴椭球建模; (3)流体动力珠建模; (4)区分各种构象类型的能力,特别是对于多分散大分子体系; (5)高分子柔韧性分析。 [参考:182]

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