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Surface enhanced fluorescence

机译:表面增强荧光

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摘要

Fluorescence is widely used in optical devices, microscopy imaging, biology, medical research and diagnosis. Improving fluorescence sensitivity, all the way to the limit of single-molecular detection needed in many applications, remains a great challenge. The technique of surface enhanced fluorescence (SEF) is based upon the design of surfaces in the vicinity of the emitter. SEF yields an overall improvement in the fluorescence detection efficiency through modification and control of the local electromagnetic environment of the emitter. Near-field coupling between the emitter and surface modes plays a crucial role in SEF. In particular, plasmonic surfaces with localized and propagating surface plasmons are efficient SEF substrates. Recent progress in tailoring surfaces at the nanometre scale extends greatly the realm of SEF applications. This review focuses on the recent advances in the different mechanisms involved in SEF, in each case highlighting the most relevant applications.
机译:荧光广泛用于光学设备,显微镜成像,生物学,医学研究和诊断。一直到许多应用中需要提高单分子检测极限的荧光灵敏度仍然是一个巨大的挑战。表面增强荧光(SEF)技术基于发射器附近表面的设计。 SEF通过修改和控制发射器的局部电磁环境,可以全面提高荧光检测效率。发射器和表面模式之间的近场耦合在SEF中起着至关重要的作用。特别地,具有局部和传播的表面等离子体激元的等离子体表面是有效的SEF基板。在纳米尺度上修整表面的最新进展极大地扩展了SEF应用领域。这篇综述着重于SEF涉及的不同机制的最新进展,每种情况都突出了最相关的应用。

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