【24h】

MiRNA in systemic lupus erythematosus

机译:系统性红斑狼疮中的miRNA

获取原文
获取原文并翻译 | 示例
           

摘要

Since their recent discovery, the small noncoding RNA known as microRNAs (miRNA) have been reported to play a major role in the physiological control of gene expression and in the pathogenesis of malignant, infectious, and autoimmune disorders. In systemic lupus erythematosus (SLE), an autoimmune disease characterized by the presence of autoantibodies to multiple antigens, the role of miRNA as post-transcriptional regulators of different aspects of the disease process has recently emerged. This article reviews the pertinent literature and mechanisms of action of miRNA that have so far been associated with the pathogenesis of SLE.
机译:自从他们最近发现以来,已经报道了称为microRNA(miRNA)的小型非编码RNA在基因表达的生理控制以及恶性,传染性和自身免疫性疾病的发病机理中起着重要作用。在系统性红斑狼疮(SLE)中,一种以多种抗原为自身抗体的自身免疫性疾病,最近出现了miRNA作为疾病过程不同方面的转录后调节因子的作用。本文回顾了迄今为止与SLE的发病机理相关的miRNA的相关文献和作用机理。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱:kefu@zhangqiaokeyan.com

京公网安备:11010802029741号 ICP备案号:京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有
  • 客服微信

  • 服务号