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首页> 外文期刊>Journal of Parasitology >DEVELOPMENT OF LARVAL SCHISTOSOMA JAPONICUM BLOCKED IN ONCOMELANIA HUPENSIS BY PRE-INFECTION WITH LARVAL EXORCHIS SP.
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DEVELOPMENT OF LARVAL SCHISTOSOMA JAPONICUM BLOCKED IN ONCOMELANIA HUPENSIS BY PRE-INFECTION WITH LARVAL EXORCHIS SP.

机译：通过预先感染幼虫EXORCHIS SP制备阻塞在钉螺中的日本血吸虫幼虫。

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摘要

Schistosomiasis continues to be a significant public health threat in the world. In the area of parasitic. diseases, it is widely considered second only to malaria as a global health problem, with an incalculable drain on the economic resources of countries where it is endemic. Schistosoma japonicum is widespread in eastern and southeastern Asia, where the amphibious snail, Oncomelania hupensis, is the intermediate host. In the present study, we found that infection of O. hupensis with the mature eggs of another trematode, Exorchis sp., inhibited development of S. japonicum mother sporocysts in O. hupensis. Exorchis sp. commonly infects the edible fish Parasilurus asotus in China, but it is harmless to humans. This discovery provides all opportunity for possible biological control of S. japonicum infection and transmission. Additionally, it has the potential to substantially reduce the impact of the global S. japonicum that is independent of antihelminthic use. The mechanisms used by Exorchis sp. to inhibit infection by S. japonicum in the snail require further investigation.
机译：血吸虫病仍然是世界上重大的公共卫生威胁。在寄生区域。疾病，它被广泛认为是仅次于疟疾的全球健康问题，对疟疾流行国家的经济资源造成了无法估量的消耗。日本血吸虫在亚洲的东部和东南部很普遍，两栖蜗牛是钉螺。在本研究中，我们发现用另一种吸虫（Exorchis sp。）的成熟卵感染了欧珀氏酵母（O. hupensis），从而抑制了欧珀氏酵母（S. japonicum）母亲孢子囊的发育。 Exorchis sp。在中国通常会感染食用鱼类芦笋，但对人类无害。该发现为日本血吸虫的感染和传播的可能生物学控制提供了所有机会。另外，它有可能显着减少不依赖于抗蠕虫药的全球日本血吸虫的影响。 Exorchis sp。使用的机制。抑制蜗牛中日本血吸虫的感染需要进一步研究。

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