...
  • 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>Journal of stroke and cerebrovascular diseases: The official journal of National Stroke Association >Preoperative Carbon Dioxide Reactivity Studies Do Not Predict the Hemodynamic Changes Seen During Carotid EndHrterectomy After Internal Carotid Artery Clamping
【24h】

Preoperative Carbon Dioxide Reactivity Studies Do Not Predict the Hemodynamic Changes Seen During Carotid EndHrterectomy After Internal Carotid Artery Clamping

机译：术前二氧化碳反应性研究不能预测颈内动脉夹闭术后颈内膜切除术期间的血流动力学变化

获取原文
获取原文并翻译 | 示例
           
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

Background and Purpose. A preoperative warning of progressive cerebral ischemia during surgery may be of use in planning carotid endarterectomy (CE),, We have set out to determine whether preoperative cerebrovascular reactivity studies predict the late hemodynamic changes detected during the procedure. Patients and Methods. Sixty-seven patients awaiting CE for high-grade carotid stenosis underwent preoperative cerebral CO-2 reactivity assessment using standard transcranial Doppler (TCD) methods. During subsequent surgery, hemodynamic changes were monitored with TCD, near-infrared spectroscopy, and a cerebral function monitor. Signals of mean MCA flow velocity (FV) and of cerebral oxyhemoglobin and deoxyhemoglobin concentration were recorded continuously, and the mean values were measured at 5, 10, and 15 minutes after internal carotid clamping. For each variable, the maximum signal change was measured 5 minutes after clamp application (Max5), and in addition the spontaneous hemodynamic recovery over the next 10 minutes (Iiec) was calculated. Scatterplots of Max5 and IIec against preoperative CO-2 reactivity indices (ipsilateral, bihemispheric mean, and interhemispheric assym-metry) were generated for correlative analysis. Results. The Max5 for oxyhemoglobin and deoxyhemoglobin were inversely related (r = -.302, P = .015). There was no relationship between ipsilateral preoperative CO-2 reactivity index and Max5 -for any intraoperative variable measured. In addition, the reactivity did not predict the hemodynamic recovery (Irec) observed during clamp application. However, the interhemispheric asymmetry did show a modest inverse correlation to Max5 FV (r = -.256, P = .046). Conclusion., Preoperative TCD cerebral CO-2 reactivity cannot be used clinically to predict the intraoperative hemodynamic changes seen during CE.
机译：背景和目的。在计划进行颈总动脉内膜切除术（CE）时可能会使用术前进行性脑缺血的术前警告。我们已着手确定术前脑血管反应性研究是否可以预测手术期间发现的晚期血液动力学变化。患者和方法。使用标准经颅多普勒（TCD）方法对等待CE的高级别颈动脉狭窄的67例患者进行术前脑CO-2反应性评估。在随后的手术中，通过TCD，近红外光谱和脑功能监测仪监测血液动力学变化。连续记录平均MCA流速（FV）信号和大脑氧合血红蛋白和脱氧血红蛋白浓度的信号，并在颈内动脉钳制后第5、10和15分钟测量平均值。对于每个变量，在施加钳夹后5分钟（Max5）测得最大信号变化，此外，还计算了接下来10分钟的自发血液动力学恢复（Iiec）。生成了Max5和IIec对术前CO-2反应性指标（同侧，双半球均值和半球间不对称性）的散点图，以进行相关分析。结果。氧合血红蛋白和脱氧血红蛋白的Max5呈负相关（r = -.302，P = .015）。对于术中测量的任何变量，同侧术前CO-2反应性指数与Max5之间没有关系。另外，反应性不能预测在钳夹期间观察到的血液动力学恢复（Irec）。但是，半球间不对称性确实显示出与Max5 FV的适度逆相关（r = -.256，P = .046）。结论：术前TCD脑CO-2反应性不能用于临床预测CE期间术中血流动力学变化。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号