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首页> 外文期刊>Journal of the American Pharmacists Association: JAPhA >Impact on medication use and adherence of Australian pharmacists' diabetes care services.
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Impact on medication use and adherence of Australian pharmacists' diabetes care services.

机译：对药物使用和澳大利亚药剂师糖尿病护理服务依从性的影响。

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OBJECTIVE: To assess the effect of a specialized service implemented in community pharmacies for patients with type 2 diabetes on medication use and medication-related problems. DESIGN: Parallel group, multisite, control versus intervention, repeated measures design, with three different regions in New South Wales, Australia, used as intervention regions, then matched with control regions as much as possible. INTERVENTION: After initial training, pharmacists followed a clinical protocol for more than 9 months, with patient contact approximately monthly. Each patient received an adherence assessment at the beginning and end of the study, adherence support, and a medication review as part of the intervention. MAIN OUTCOME MEASURES: Risk of nonadherence using Brief Medication Questionnaire (BMQ) scores and changes to medication regimen. RESULTS: Compared with 82 control patients, 106 intervention patients with similar demographic and clinical characteristics had significantly improved self-reported nonadherence as reflected in total BMQ scores after 9 months. The mean (+/-SD) number of medications prescribed at follow-up in intervention participants decreased significantly, from 8.2+/-3.0 to 7.7+/-2.7. No reduction was observed among the control patients (7.6+/-2.4 and 7.3+/-2.4). The overall prevalence of changes to the regimen was also significantly higher in the intervention group (51%) compared with controls (40%). CONCLUSION: Community pharmacists trained in medication review and using protocols in collaboration with providers improved adherence in patients with type 2 diabetes, reduced problems patients had in accessing their medications, and recommended medication regimen changes that improved outcomes.
机译：目的：评估社区药房为2型糖尿病患者提供的专门服务对药物使用和药物相关问题的影响。设计：平行组，多地点，控制与干预，重复措施设计，将澳大利亚新南威尔士州的三个不同区域用作干预区域，然后尽可能与控制区域匹配。干预：初步培训后，药剂师遵循临床方案进行了9个月以上，患者每月约有一次接触。每个患者在研究开始和结束时均接受依从性评估，依从性支持和药物复查作为干预措施的一部分。主要观察指标：使用简易药物调查表（BMQ）评分和药物治疗方案变更的不依从风险。结果：与82例对照患者相比，106例具有相似人口统计学和临床​​特征的干预患者在9个月后的BMQ总得分中反映出自我报告的不依从性得到了显着改善。干预参与者随访时开出的平均（+/- SD）药物数量显着下降，从8.2 +/- 3.0降低到7.7 +/- 2.7。在对照患者中没有观察到减少（7.6 +/- 2.4和7.3 +/- 2.4）。与对照组（40％）相比，干预组（51％）的方案变更总体患病率也明显更高。结论：接受过药物审查和与提供者合作使用方案的培训的社区药剂师可改善2型糖尿病患者的依从性，减少患者在用药过程中遇到的问题，并建议更改用药方案以改善结局。

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