IRRITABLE BOWEL SYNDROME: Rational Therapy

NICHOLAS J. TALLEY

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IRRITABLE BOWEL SYNDROME: Rational Therapy

机译：肠易激综合症：合理治疗

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Irritable bowel syndrome (IBS) is characterized by abdominal pain or discomfort, bloating, and constipation or diarrhea; the pain is typically relieved by defecation. The diagnosis is not one of exclusion; it can be made based on the answers to a few key questions and the absence of "alarm" symptoms. Judicious use of fiber supplements, the elimination of particular foods, and regulation of bowel function can help relieve symptoms. Polyethylene glycol or lubi-prostone can be used to treat IBS with constipation. Loperamide land If symptoms are severe, alosetron) are of benefit in IBS with diarrhea (although alosetron carries a small risk of ischemic colitis and severe constipation). Antidepres-sants (both trlcyclics and selective serotonin reuptake inhibitors) may be used to treat IBS. Probiotic therapy or rifaximin may help reduce IBS symptoms including bloating.

机译：肠易激综合症（IBS）的特征是腹痛或不适，腹胀，便秘或腹泻。排便通常可以缓解疼痛。诊断不是排除之一;它可以根据一些关键问题的答案以及不存在“警报”症状的情况来做出。明智地使用纤维补充剂，消除某些食物以及调节肠功能可以帮助缓解症状。聚乙二醇或鲁比前列酮可用于治疗便秘的IBS。洛哌丁胺类药物如果症状严重，腹泻型IBS有益于阿洛司琼（尽管阿洛司琼的缺血性结肠炎和严重便秘的风险较小）。抗抑郁药（三环类和选择性5-羟色胺再摄取抑制剂）可用于治疗IBS。益生菌疗法或利福昔明可能有助于减轻IBS症状，包括腹胀。

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《Consultant.》 |2011年第6期|共7页
作者
NICHOLAS J. TALLEY;
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正文语种 eng
中图分类医药、卫生;
关键词
irritable bowel syndrome; diarrhea; constipation; abdominal pain; fiber therapy; alosetron; rifaximin; probiotics;

机译：肠易激综合征;腹泻;便秘;腹痛;纤维疗法;阿洛司琼;利福昔明;益生菌;

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1. The Irritable Bowel Syndrome Outcome Study (IBSOS): Rationale and design of a randomized, placebo-controlled trial with 12month follow up of self- versus clinician-administered CBT for moderate to severe irritable bowel syndrome [J] . LacknerJ.M., KeeferL., JaccardJ., Contemporary clinical trials . 2012,第6期

机译：肠易激综合症结果研究（IBSOS）：对中度至重度肠易激综合症进行自我和临床对照CBT随访12个月的随机，安慰剂对照试验的原理和设计
2. Assessing Cognitive behavioural Therapy in Irritable Bowel (ACTIB): protocol for a randomised controlled trial of clinical-effectiveness and cost-effectiveness of therapist delivered cognitive behavioural therapy and web-based self-management in irritable bowel syndrome in adults [J] . Alice Sibelli, Felicity L Bishop, Gilly OReilly, BMJ Open . 2015,第7期

机译：评估肠易激综合征的认知行为疗法（ACTIB）：治疗师在成人肠易激综合征中进行认知行为疗法和基于网络的自我管理的临床有效性和成本效益的随机对照试验方案
3. Assessing Cognitive behavioural Therapy in Irritable Bowel (ACTIB): protocol for a randomised controlled trial of clinical-effectiveness and cost-effectiveness of therapist delivered cognitive behavioural therapy and web-based self-management in irritable bowel syndrome in adults [J] . Alice Sibelli, Felicity L Bishop, Gilly OReilly, BMJ Open . 2015,第7期

机译：评估肠易激综合征的认知行为疗法（ACTIB）：治疗师在成人肠易激综合征中进行认知行为疗法和基于网络的自我管理的临床有效性和成本效益的随机对照试验方案
4. State-of-the Art Lecture: Irritable bowel syndrome: the new inflammatory bowel disease? [C] . R. C. SPILLE Falk Symposium . 2006

机译：最先进的讲座：肠易激综合征：新的炎症性肠病？
5. Heart Rate Variability Biofeedback Therapy versus Cognitive Therapy for Irritable Bowel Syndrome: A study of attendance, compliance, and symptom improvement. [D] . Thompson, Megan. 2010

机译：心率变异性生物反馈疗法与认知疗法对肠易激综合征的研究：出勤，依从性和症状改善的研究。
6. The Irritable Bowel Syndrome Outcome Study (IBSOS): Rationale and design of a randomized placebo-controlled trial with 12 month follow up of self- versus clinician-administered CBT for moderate to severe irritable bowel syndrome [O] . Jeffrey M. Lackner, Laurie Keefer, James Jaccard, -1

机译：肠易激综合征结果研究（IBSOS）：基本原理和设计随机安慰剂对照试验12个月的自我与临床医生 - 临床医生的CBT中度急剧肠道症综合征
7. The Irritable Bowel Syndrome Outcome Study (IBSOS): Rationale and design of a randomized, placebo-controlled trial with 12month follow up of self- versus clinician-administered CBT for moderate to severe irritable bowel syndrome [O] . Jeffrey M. Lackner, Laurie Keefer, James Jaccard, 2012

机译：肠易激综合征结果研究（IBSOS）：对随机，安慰剂对照试验的基本原理和设计，与12个月跟进自我与临床医生 - 临床医生的CBT中度至重度肠易激综合征

IRRITABLE BOWEL SYNDROME: Rational Therapy

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