New iodinated quinoline-2-carboxamides for SPECT imaging of the translocator protein.

Stevenson L; Tavares AA; Brunet

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New iodinated quinoline-2-carboxamides for SPECT imaging of the translocator protein.

机译：新的碘化喹啉-2-羧酰胺用于SPECT易位蛋白的成像。

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With the aim of developing new SPECT imaging agents for the translocator protein (TSPO), a small library of iodinated quinoline-2-carboxamides have been prepared and tested for binding affinity with TSPO. N,N-Diethyl-3-iodomethyl-4-phenylquinoline-2-carboxamide was found to have excellent affinity (K(i) 12.0 nM), comparable to that of the widely used TSPO imaging agent PK11195.

机译：为了开发用于转运蛋白（TSPO）的新型SPECT显像剂，已制备了一个小的碘化喹啉-2-羧酰胺文库，并测试了与TSPO的结合亲和力。与广泛使用的TSPO成像剂PK11195相比，N，N-二乙基-3-碘甲基-4-苯基喹啉-2-羧酰胺具有极好的亲和力（K（i）12.0 nM）。

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《Bioorganic and Medicinal Chemistry Letters》 |2010年第3期|共4页
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Stevenson L; Tavares AA; Brunet;
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1. New iodinated quinoline-2-carboxamides for SPECT imaging of the translocator protein. [J] . Stevenson L, Tavares AA, Brunet Bioorganic and Medicinal Chemistry Letters . 2010,第3期

机译：新的碘化喹啉-2-羧酰胺用于SPECT易位蛋白的成像。
2. The Variability of Translocator Protein Signal in Brain and Blood of Genotyped Healthy Humans Using In Vivo 123I-CLINDE SPECT Imaging: A Test-Retest Study [J] . Ling Feng, Per Jensen, Gerda Thomsen, The Journal of Nuclear Medicine . 2017,第6期

机译：体内123I-CLINDE SPECT成像技术在基因型健康人的大脑和血液中易位蛋白信号的变异性：一项再测试研究
3. The Variability of Translocator Protein Signal in Brain and Blood of Genotyped Healthy Humans Using In Vivo I-123-CLINDE SPECT Imaging: A Test-Retest Study [J] . Feng Ling, Jensen Per, Thomsen Gerda, The Journal of Nuclear Medicine . 2017,第6期

机译：在体内I-123-Clinde Spect成像中使用基因分型健康人类脑和血液中易偶蛋白信号的变异性：测试重新测试
4. First Imaging Data with C-SPECT: A Dedicated Human Cardiac SPECT Imager [C] . Scott D. Metzler, Poopalasingam Sankar, Dale J. Stentz, IEEE Nuclear Science Symposium;Medical Imaging Conference . 2018

机译：使用C-SPECT的首批成像数据：专用的人心SPECT成像仪
5. Limited-field-of-view MR/SPECT for small animal imaging and development of a Keyhole SPECT image reconstruction method using a priori information. [D] . Lee, Keum Sil. 2010

机译：用于小动物成像的受限视场MR / SPECT，以及使用先验信息开发的Keyhole SPECT图像重建方法。
6. Radiosynthesis In Vivo Biological Evaluation and Imaging of Brain Lesions with 123I-CLINME a New SPECT Tracer for the Translocator Protein [O] . F. Mattner, M. Quinlivan, I. Greguric, 2015

机译：123I -CLINME一种新的SPECT示踪剂用于转运蛋白的放射性合成体内生物学评估和脑部病变成像
7. Cover Picture: BZM055, an Iodinated Radiotracer Candidate for PET and SPECT Imaging of Myelin and FTY720 Brain Distribution (ChemMedChem 4/2011) [O] . Emmanuelle Briard, David Orain, Christian Beerli, 2011

机译：封面图片：BZM055，米尔辛和FTY720大脑分布的宠物和SPECT成像的碘化射频机构候选者（ChemMedchem 4/2011）

New iodinated quinoline-2-carboxamides for SPECT imaging of the translocator protein.

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