The use of a peptidic scaffold for the formation of stable guanine tetrads: Control of a H-bonded pattern in water

Murat P.; Gennaro B.; Garcia J.; Spinelli N.; Dumy P.; Defrancq E.

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The use of a peptidic scaffold for the formation of stable guanine tetrads: Control of a H-bonded pattern in water

机译：使用肽类支架形成稳定的鸟嘌呤四联体：控制水中的H键模式

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With a little help from a scaffold: The pre-organization of guanine units onto a peptidic scaffold allows a remarkable stabilization of the G-quartet motif (see graphic). Indeed, the quartet motif was found to be stable even in water without addition of salts. The present study shows the first formation of a single synthetic G-tetrad under these aqueous conditions.

机译：在支架的帮助下：将鸟嘌呤单位预先组织到肽支架上，可以显着稳定G四重奏图案（见图）。实际上，发现四重奏图案甚至在不添加盐的水中也是稳定的。本研究表明在这些水性条件下首次形成单个合成G-tetrad。

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《Chemistry: A European journal》 |2011年第21期|共5页
作者
Murat P.; Gennaro B.; Garcia J.; Spinelli N.; Dumy P.; Defrancq E.;
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正文语种 eng
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关键词
cyclodecapeptide; G-quartets; hydrogen bonds; scaffolds; supramolecular chemistry;

机译：环十肽;G四联体;氢键;支架;超分子化学;

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1. The Use of a Peptidic Scaffold for the Formation of Stable Guanine Tetrads: Control of a H-bonded Pattern in Water [J] . Pierre Murat Béatrice Gennaro Prof. Julian Garcia Dr. Nicolas Spinelli Prof. Pascal Dumy Prof. Eric Defrancq Chemistry - A European Journal . 2011,第21期

机译：使用肽支架形成稳定的鸟嘌呤四联体：在水中的H键模式的控制。
2. G-quadruplexes with (4n-1) guanines in the G-tetrad core: formation of a G-triad center dot water complex and implication for small-molecule binding [J] . Heddi Brahim, Martin-Pintado Nerea, Serimbetov Zhalgas, Nucleic Acids Research . 2016,第2期

机译：G-四联体核心中具有（4n-1）鸟嘌呤的G-四联体：G-三联体中心点水络合物的形成及其对小分子结合的影响
3. G-quadruplexes with (4n-1) guanines in the G-tetrad core: formation of a G-triad center dot water complex and implication for small-molecule binding [J] . Heddi Brahim, Martin-Pintado Nerea, Serimbetov Zhalgas, Nucleic Acids Research . 2016,第2期

机译：G-四联体核心中具有（4n-1）鸟嘌呤的G-四联体：G-三联体中心点水络合物的形成及其对小分子结合的影响
4. Harnessing the flexibility of peptidic scaffolds to control their copper(II) coordination properties [C] . Fragoso A., Lamosa P., Delgado R., European Biological Inorganic Chemistry Conference . 2012

机译：利用肽支架的灵活性来控制其铜（II）配位性能
5. Controlled vascular cellular growth by microstructure patterned surfaces on implantable biodegradable polymer scaffold. [D] . Garg, Nitin. 2009

机译：通过可植入的可生物降解的聚合物支架上的微结构图案化表面来控制血管细胞的生长。
6. G-quadruplexes with (4n - 1) guanines in the G-tetrad core: formation of a G-triad·water complex and implication for small-molecule binding [O] . Brahim Heddi, Nerea Martín-Pintado, Zhalgas Serimbetov, 2016

机译：G-四联核中带有（4n-1）鸟嘌呤的G-四联体：G-三联体·水复合物的形成及其对小分子结合的影响
7. H-Bonding Patterns in the Platinated Guanine-Cytosine Base Pair and Guanine-Cytosine-Guanine-Cytosine Base Tetrad: an Electron Density Deformation Analysis and AIM Study [O] . -1

机译：在丁基鸟嘌呤 - 胞嘧啶碱基对中的H键合图案和鸟嘌呤 - 胞嘧啶 - 鸟嘌呤 - 胞嘧啶基础四边形：电子密度变形分析和瞄准研究
8. THE EFFECT OF VARIATIONS IN INTERNAL POWER PATTERN ON COALITION FORMATION IN TETRADS. [R] . Loyda M. Shears 1965

机译：内部电力模式的变化对TETRaDs中煤层形成的影响。

The use of a peptidic scaffold for the formation of stable guanine tetrads: Control of a H-bonded pattern in water

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