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首页> 外文期刊>Chemistry: A European journal >One-dimensional magnetic nanowires obtained by protein fibril biotemplating
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One-dimensional magnetic nanowires obtained by protein fibril biotemplating

机译：通过蛋白原纤维生物模板制备的一维磁性纳米线

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摘要

Magnetic nanowires were obtained through the in situ synthesis of magnetic material by Fe-controlled nanoprecipitation in the presence of two different protein (human serum albumin (HSA) and lysozyme (Lys)) fibrils as biotemplating agents. The structural characteristics of the biotemplates were transferred to the hybrid magnetic wires. They exhibited excellent magnetic properties as a consequence of the 1D assembly and fusion of magnetite nanoparticles as ascertained by SQUID magnetometry. Prompted by these findings, we also checked their potential applicability as MRI contrast agents. The magnetic wires exhibited large r_2* relaxivities and sufficient contrast resolution even in the presence of an extremely small amount of Fe in the magnetic hybrids, which would potentially enable their use as T_2 contrast imaging agents.
机译：通过在两种不同的蛋白质（人血清白蛋白（HSA）和溶菌酶（Lys））原纤维作为生物模板剂的存在下，通过铁控制的纳米沉淀原位合成磁性材料获得磁性纳米线。生物模板的结构特征被转移到混合电磁线上。由于SQUID磁力测定法确定了磁铁矿纳米粒子的一维组装和融合，因此它们具有出色的磁性。根据这些发现，我们还检查了它们作为MRI造影剂的潜在适用性。即使在磁性杂化物中存在极少量的铁时，电磁线也表现出大的r_2 *弛豫度和足够的对比度分辨率，这将有可能使其用作T_2造影剂。

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