首页> 外文期刊>Chemistry: A European journal >Carbon dots prepared by hydrothermal treatment of dopamine as an effective fluorescent sensing platform for the label-free detection of iron(III) ions and dopamine
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Carbon dots prepared by hydrothermal treatment of dopamine as an effective fluorescent sensing platform for the label-free detection of iron(III) ions and dopamine

机译:通过多巴胺水热处理制备的碳点作为有效的荧光传感平台,用于无标记的铁(III)离子和多巴胺检测

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摘要

A facile, economic and green one-step hydrothermal synthesis route using dopamine as source towards photoluminescent carbon nanoparticles (CNPs) is proposed. The as-prepared CNPs have an average size about 3.8nm. The emission spectra of the CNPs are broad, ranging from approximately 380 (purple) to approximately 525nm (green), depending on the excitation wavelengths. Due to the favorable optical properties, the CNPs can readily enter into A549 cells and has been used for multicolor biolabeling and bioimaging. Most importantly, the as-prepared CNPs contain distinctive catechol groups on their surfaces. Due to the special response of catechol groups to Fe~(3+) ions, we further demonstrate that such wholly new CNPs can serve as a very effective fluorescent sensing platform for label-free sensitive and selective detection of Fe ~(3+) ions and dopamine with a detection limit as low as 0.32μM and 68nM, respectively. The new "mix-and-detect" strategy is simple, green, and exhibits high sensitivity and selectivity. The present method was also applied to the determination of Fe3+ ions in real water samples and dopamine in human urine and serum samples successfully.
机译:提出了一种简单,经济,绿色的多步水热合成路线,以多巴胺为光致发光纳米碳(CNPs)来源。所制备的CNP具有约3.8nm的平均尺寸。 CNP的发射光谱范围很广,取决于激发波长,范围从大约380(紫色)到大约525nm(绿色)。由于良好的光学性能,CNP可以轻松进入A549细胞,并已用于多色生物标记和生物成像。最重要的是,所制备的CNP在其表面上含有独特的邻苯二酚基团。由于邻苯二酚基团对Fe〜(3+)离子的特殊反应,我们进一步证明了这种全新的CNP可以作为非常有效的荧光传感平台,用于无标记的Fe〜(3+)离子的选择性检测。和多巴胺的检出限分别低至0.32μM和68nM。新的“混合和检测”策略简单,绿色,并具有很高的灵敏度和选择性。本方法也成功地用于测定真实水样中的Fe3 +离子以及人尿和血清中的多巴胺。

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