Prefolded Synthetic G-Quartets Display Enhanced Bioinspired Properties

Flack Theodore; Constantin Thibaut; Penasse Sylvain; Dejeu Jerome; Gennaro Beatrice; Jourdan Muriel; Laguerre Aurelien; Pirrotta Marc; Monchaud David; Spinelli Nicolas; Defrancq Eric

首页> 外文期刊>Chemistry: A European journal >Prefolded Synthetic G-Quartets Display Enhanced Bioinspired Properties

【24h】

Prefolded Synthetic G-Quartets Display Enhanced Bioinspired Properties

机译：预折叠的合成G四重奏显示增强的生物启发性质

获取原文

获取原文并翻译 | 示例

掌桥外文数据库（机构版） >>

开具论文收录证明 >>

文献代查 >>

页面导航

摘要
著录项
相似文献
相关主题

摘要

A water-soluble template-assembled synthetic G-quartet (TASQ) based on the use of a macrocyclodecapeptide scaffold was designed to display stable intramolecular folds alone in solution. The preformation of the guanine quartet, demonstrated by NMR and CD investigations, results in enhanced peroxidase-type biocatalytic activities and improved quadruplex-interacting properties. Comparison of its DNAzyme-boosting properties with the ones of previously published TASQ revealed that, nowadays, it is the best DNAzyme-boosting agent.

机译：基于使用大环十肽支架的水溶性模板组装合成G四联体（TASQ）被设计为在溶液中单独显示稳定的分子内折叠。通过NMR和CD研究证明，鸟嘌呤四方体的预形成导致增强的过氧化物酶型生物催化活性和改善的四链体相互作用特性。将其DNAzyme增强特性与以前发布的TASQ进行比较后发现，它是当今最好的DNAzyme增强剂。

著录项

来源
《Chemistry: A European journal》 |2016年第5期|共8页
作者
Flack Theodore; Constantin Thibaut; Penasse Sylvain; Dejeu Jerome; Gennaro Beatrice; Jourdan Muriel; Laguerre Aurelien; Pirrotta Marc; Monchaud David; Spinelli Nicolas; Defrancq Eric;
展开▼
作者单位

展开▼
收录信息
原文格式 PDF
正文语种 eng
中图分类
关键词
cyclodecapeptide; DNAzyme; G-quadruplexes; G-quartets; supramolecular chemistry;

机译：环十肽;DNA酶;G-四链体;G-四元体;超分子化学;

相似文献

外文文献
中文文献
专利

1. Prefolded Synthetic G-Quartets Display Enhanced Bioinspired Properties [J] . Flack Theodore, Constantin Thibaut, Penasse Sylvain, Chemistry: A European journal . 2016,第5期

机译：预折叠的合成G四重奏显示增强的生物启发性质
2. A bioinspired, ice-templated multifunctional 3D cryogel composite crosslinked through in situ reduction of GO displayed improved mechanical, osteogenic and antimicrobial properties [J] . Chopra Vianni, Thomas Jijo, Sharma Anjana, Materials science & engineering . 2021,第Feba期

机译：通过原位减少展开机械，成骨和抗微生物性能，通过原位减少交联的Bioinspired，冰模拟的多功能3D Cryogel复合材料
3. Spin Valve Devices With Synthetic-Ferrimagnet Free-Layer Displaying Enhanced Sensitivity for Nanometric Sensors [J] . Coelho P., Leitao D.C., Antunes J., Magnetics, IEEE Transactions on . 2014,第11期

机译：具有合成铁磁性自由层的自旋阀装置，对纳米传感器具有更高的灵敏度
4. Challenges with displaying Enhanced and Synthetic Vision video on a Head-up Display [C] . Peter J Howells, Robert Brown Enhanced and Synthetic Vision 2007; Proceedings of SPIE-The International Society for Optical Engineering; vol.6559 . 2007

机译：在平视显示器上显示增强和合成视觉视频面临的挑战
5. Engineering synthetic bone graft substitutes with improved mechanical properties, enhanced bioactivity, and on-demand growth factor delivery. [D] . Meagher, Matthew J. 2015

机译：工程合成的骨移植替代品，具有改善的机械性能，增强的生物活性和按需生长因子传递的功能。
6. Herpes simplex virus type 1 thymidine kinase–armed bovine herpesvirus type 4–based vector displays enhanced oncolytic properties in immunocompetent orthotopic syngenic mouse and rat glioma models [O] . Marco Redaelli, Valentina Franceschi, Antonio Capocefalo, 2012

机译：单纯疱疹病毒1型胸腺嘧啶激酶武装的4型牛疱疹病毒载体在具有免疫功能的原位同基因小鼠和大鼠神经胶质瘤模型中的溶瘤特性增强
7. Tribology Properties: Laser Irradiation-Induced SiC@Graphene Sub-Microspheres: A Bioinspired Core-Shell Structure for Enhanced Tribology Properties (Adv. Mater. Interfaces 5/2018) [O] . Ting Luo, Xinchun Chen, Ping Wang, 2018

机译：摩擦学特性：激光辐照诱导的SiC @石墨烯亚微球：用于增强摩擦学性质的生物悬浮芯壳结构（ADV。母体。接口5/2018）
8. Enhanced/Synthetic Vision and Head-Worn Display Technologies for Terminal Maneuvering Area NextGen Operations [R] . Arthur, J. J., Prinzell, L. J., Williams, S. P., 2011

机译：用于终端机动区NextGen操作的增强/合成视觉和头戴式显示技术

Prefolded Synthetic G-Quartets Display Enhanced Bioinspired Properties

摘要

著录项

相似文献

相关主题

期刊订阅