• 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>American Journal of Physiology >Hypocapnia reduces the T wave of the electrocardiogram in normal human subjects.
【24h】

Hypocapnia reduces the T wave of the electrocardiogram in normal human subjects.

机译：低碳酸血症会降低正常人的心电图的T波。

获取原文
获取原文并翻译 | 示例
           
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

During voluntary hyperventilation in unanesthetized humans, hypocapnia causes coronary vasoconstriction and decreased oxygen (O(2)) supply and availability to the heart. This can induce local epicardial coronary artery spasm in susceptible patients. Its diagnostic potential for detection of early heart disease is unclear. This is because such hypocapnia produces an inconsistent and irreproducible effect on electrocardiogram (ECG) in healthy subjects. To resolve this inconsistency, we have applied two new experimental techniques in normal, healthy subjects to measure the effects of hypocapnia on their ECG: mechanical hyperventilation and averaging of multiple ECG cycles. In 15 normal subjects, we show that hypocapnia (20 +/- 1 mmHg) significantly reduced mean T wave amplitude by 0.1 +/- 0.0 mV. Hypocapnia also increased mean heart rate by 4 beats/min without significantly altering blood pressure, ionized calcium or potassium levels, or the R wave or other features of the ECG. We therefore provide the first unequivocal demonstration that hypocapnia does consistently reduce T wave amplitude in normal, healthy subjects.
机译：在未麻醉的人中自愿过度换气期间，低碳酸血症会导致冠状动脉血管收缩并降低心脏的氧气（O（2））供应和可用性。这可以在易感患者中引起局部心外膜冠状动脉痉挛。目前尚不清楚其对早期心脏病的诊断潜力。这是因为这种低碳酸血症会对健康受试者的心电图（ECG）产生不一致且不可再现的影响。为了解决这种矛盾，我们在正常健康受试者中应用了两种新的实验技术来测量低碳酸血症对其心电图的影响：机械通气和平均多个心电图周期。在15名正常受试者中，我们显示出低碳酸血症（20 +/- 1 mmHg）显着降低了平均T波振幅0.1 +/- 0.0 mV。低碳酸血症还会使平均心率增加4次/分钟，而不会显着改变血压，离子钙或钾水平或R波或ECG的其他特征。因此，我们提供了第一个明确的证据，即低碳酸血症确实会持续降低正常健康受试者的T波幅度。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号