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首页> 外文期刊>Anticancer Research: International Journal of Cancer Research and Treatment >Urological Procedures in Patients with Peritoneal Carcinomatosis of Colorectal Cancer Treated with HIPEC: Morbidity and Survival Analysis
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Urological Procedures in Patients with Peritoneal Carcinomatosis of Colorectal Cancer Treated with HIPEC: Morbidity and Survival Analysis

机译：HIPEC治疗大肠癌腹膜癌的泌尿外科程序：发病率和生存率分析

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Aim: To investigate whether cytoreductive surgery and hyperthermic intraperitoneal chemotherapy (CRS+HIPEC) is a feasible and effective option for patients with urological involvement of peritoneal carcinomatosis from colorectal cancer (CRC-PC). Patients and Methods: The characteristics of patients with CRC-PC treated with CRS+HIPEC, with or without a urological procedure, between April 2005 and June 2013 in two tertiary Centres were analyzed. Results: Thirty-eight patients (14%) out of 267 CRC-PC patients treated with CRS+HIPEC had a urological procedure during cytoreduction. The median survival was not significantly different between patients with or without a urological procedure (26.9 versus 32.1 months, p=0.29). Severe complications occurred more in patients with a urological procedure (47% versus 20%, p<0.001). In patients with a urological procedure, the most frequent complications were gastrointestinal leakage (n=9) and intra-abdominal abscess formation (n=5). Conclusion: Urological resections as a part of CRS+HIPEC in patients with peritoneal carcinomatosis of colorectal origin are feasible and effective. Severe complications are prevalent in these patients but survival is comparable to patients without involvement of the urinary system.
机译：目的：研究对于患有大肠癌腹膜癌病（CRC-PC）泌尿外科疾病的患者，进行细胞减灭术和高温腹膜内化疗（CRS + HIPEC）是否是可行和有效的选择。患者与方法：分析了2005年4月至2013年6月在两个大专科医院接受或不接受泌尿外科手术的CRS + HIPEC治疗的CRC-PC患者的特征。结果：在267例接受CRS + HIPEC治疗的CRC-PC患者中，有38例（14％）在细胞减少过程中进行了泌尿外科手术。在有或没有泌尿外科手术的患者之间，中位生存期无显着差异（26.9 vs 32.1个月，p = 0.29）。泌尿外科手术患者发生的严重并发症更多（47％比20％，p <0.001）。在泌尿外科手术的患者中，最常见的并发症是胃肠道渗漏（n = 9）和腹腔内脓肿形成（n = 5）。结论：对于大肠源性腹膜癌患者，尿路切除术作为CRS + HIPEC的一部分是可行和有效的。严重并发症在这些患者中普遍存在，但其存活率与不涉及泌尿系统的患者相当。

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