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Variations of AbaR4-type resistance islands in Acinetobacter baumannii isolates from South Korea

机译:韩国鲍曼不动杆菌中AbaR4型抗性岛的变异

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摘要

AbaR resistance islands in Acinetobacter baumannii isolates from South Korea were investigated. AbaR4-type resistance islands, including bla OXA-23-containing Tn2006, interrupted the comM gene in A. baumannii ST75 isolates. However, Tn2006 was not identified within AbaR resistance islands of ST138 isolates, although the bla OXA-23 gene was detected in them. The similar structures of resistance islands suggest that most carbapenem-resistant A. baumannii isolates in South Korea have originated from the same ancestor with a globally disseminated clone, GC II.
机译:调查了来自韩国的鲍曼不动杆菌中的AbaR抵抗岛。 AbaR4型抗性岛,包括含bla OXA-23的Tn2006,中断了鲍曼不动杆菌ST75分离物中的comM基因。然而,尽管在其中检测到了bla OXA-23基因,但在ST138分离株的AbaR抗性岛内未鉴定到Tn2006。相似的抗性岛结构表明,韩国大多数对碳青霉烯类耐药的鲍曼不动杆菌菌株均来自与全球分布的克隆GC II相同的祖先。

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