Assessment of the induction of dormant ring stages in Plasmodium falciparum parasites by artemisone and artemisone entrapped in Pheroid vesicles in vitro

GroblerL.; ChavchichM.; HaynesR.K.; EdsteinM.D.; GroblerA.F.

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Assessment of the induction of dormant ring stages in Plasmodium falciparum parasites by artemisone and artemisone entrapped in Pheroid vesicles in vitro

机译：青蒿素和青蒿素包裹在类脂囊泡中体外评估恶性疟原虫寄生虫休眠期的诱导

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The in vitro antimalarial activities of artemisone and artemisone entrapped in Pheroid vesicles were compared, as was their ability to induce dormancy in Plasmodium falciparum. There was no increase in the activity of artemisone entrapped in Pheroid vesicles against multidrug-resistant P. falciparum lines. Artemisone induced the formation of dormant ring stages similar to dihydroartemisinin. Thus, the Pheroid delivery system neither improved the activity of artemisone nor prevented the induction of dormant rings.

机译：比较了青蒿素和包裹在类固醇囊中的青蒿素的体外抗疟活性，以及它们在恶性疟原虫中诱导休眠的能力。呈蛇药囊泡的青蒿素对多药耐药恶性疟原虫品系的活性没有增加。青蒿素诱导了类似于二氢青蒿素的休眠环阶段的形成。因此，类固醇递送系统既没有提高青蒿素的活性，也没有阻止诱导休眠环。

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《Antimicrobial agents and chemotherapy.》 |2014年第12期|共4页
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GroblerL.; ChavchichM.; HaynesR.K.; EdsteinM.D.; GroblerA.F.;
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1. Assessment of the induction of dormant ring stages in Plasmodium falciparum parasites by artemisone and artemisone entrapped in Pheroid vesicles in vitro [J] . GroblerL., ChavchichM., HaynesR.K., Antimicrobial agents and chemotherapy. . 2014,第12期

机译：青蒿素和青蒿素包裹在类脂囊泡中体外评估恶性疟原虫寄生虫休眠期的诱导
2. Artemisone and Artemiside Are Potent Panreactive Antimalarial Agents That Also Synergize Redox Imbalance in Plasmodium falciparum Transmissible Gametocyte Stages [J] . Coertzen Dina, Reader Janette, van der Watt Mariette, Antimicrobial agents and chemotherapy. . 2018,第8期

机译：奥尔胺和青蒿素是有效的全重复性抗疟剂，也可以在恶性疟原虫传播式配音阶段中的氧化还原性失衡促进氧化还原性抗疟疾剂
3. In vitro activity of artemisone compared with artesunate against Plasmodium falciparum. [J] . Ramharter M, Burkhardt D, Nemeth J, The American Journal of Tropical Medicine and Hygiene . 2006,第4期

机译：与青蒿琥酯相比，青蒿素对恶性疟原虫的体外活性。
4. Continuous force-displacement relationships for the human red blood cell at different erythrocytic developmental stages of Plasmodium falciparum malaria parasite [C] . John P. Mills, Lan Qie, Ming Dao, Symposium on Mechanical Properties of Bioinspired and Biological Materials . 2005

机译：在疟原虫疟原虫不同红细胞发育阶段的人红细胞连续力 - 位移关系
5. The characterization of Plasmodium falciparum iron regulatory-like protein (PfIRPa) in asexual stage Plasmodium falciparum parasites. [D] . Hodges, Marcus G. 2005

机译：无性疟原虫恶性疟原虫中恶性疟原虫铁调节样蛋白（PfIRPa）的表征。
6. Assessment of the Induction of Dormant Ring Stages in Plasmodium falciparum Parasites by Artemisone and Artemisone Entrapped in Pheroid Vesicles In Vitro [O] . Lizette Grobler, Marina Chavchich, Richard K. Haynes, 2014

机译：青蒿素和青蒿素包裹在类固醇囊泡中体外评估恶性疟原虫寄生虫休眠期的诱导
7. In vitro activity of Pheroid vesicles containing antibiotics against Plasmodium falciparum [O] . Du Plessis, Lissinda H., Van Niekerk, Anel C., Maritz, Marlene M., 2012

机译：含抗生素的恶性疟原虫卵泡囊的体外活性
8. Ex Vivo Activity of Endoperoxide Antimalarials, Including Artemisone and Arterolane, against Multidrug-Resistant Plasmodium falciparum Isolates from Cambodia. [R] . Lanteri, C. A., Chaorattanakawee, S., Lon, C., 2014

机译：内源过氧化物抗疟药（包括艾蒿酮和赤藓）对来自柬埔寨的多重耐药恶性疟原虫分离株的体外活性。

Assessment of the induction of dormant ring stages in Plasmodium falciparum parasites by artemisone and artemisone entrapped in Pheroid vesicles in vitro

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