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Diffuse optical tomography system to image brain activation with improved spatial resolution and validation with functional magnetic resonance imaging

机译:漫射光学层析成像系统以增强的空间分辨率为大脑活动成像,并通过功能磁共振成像进行验证

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摘要

Although most current diffuse optical brain imaging systems use only nearest-neighbor measurement geometry, the spatial resolution and quantitative accuracy of the imaging can be improved through the collection of overlapping sets of measurements. A continuous-wave diffuse optical imaging system that combines frequency encoding with time-division multiplexing to facilitate overlapping measurements of brain activation is described. Phantom measurements to confirm the expected improvement in spatial resolution and quantitative accuracy are presented. Experimental results showing the application of this instrument for imaging human brain activation are also presented. The observed improvement in spatial resolution is confirmed by functional magnetic resonance imaging.
机译:尽管大多数当前的漫射光学脑成像系统仅使用最邻近的测量几何体,但是可以通过收集重叠的测量集来提高成像的空间分辨率和定量精度。描述了一种连续波漫射光学成像系统,该系统将频率编码与时分多路复用相结合以促进大脑激活的重叠测量。提出了幻影测量,以确认预期的空间分辨率和定量精度的提高。实验结果显示了该仪器在成像人脑激活中的应用。功能磁共振成像证实了观察到的空间分辨率的提高。

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