Implementation of the Prostate Cancer Prevention Trial (PCPT).

Goodman PJ; Tangen CM; Crowley JJ; Carlin SM; Ryan A; Coltman CA Jr; Ford LG; Thompson IM

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Implementation of the Prostate Cancer Prevention Trial (PCPT).

机译：前列腺癌预防试验（PCPT）的实施。

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The Prostate Cancer Prevention Trial is a randomized double blind chemoprevention trial of 18,882 men. It is designed to test the difference in the histologically proven prostate cancer prevalence between a group of participants given finasteride and another given placebo for 7 years. We present an overview of the study design, details of the administrative structure of the study and a description of the successful implementation of the accrual phase.

机译：前列腺癌预防试验是一项针对18,882名男性的随机双盲化学预防试验。它旨在测试一组接受非那雄胺和另一组接受安慰剂的参与者持续7年的组织学证实的前列腺癌患病率之间的差异。我们对研究设计进行了概述，对研究的行政结构进行了详细说明，并对应计阶段的成功实施进行了描述。

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《Controlled clinical trials》 |2004年第2期|共20页
作者
Goodman PJ; Tangen CM; Crowley JJ; Carlin SM; Ryan A; Coltman CA Jr; Ford LG; Thompson IM;
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原文格式 PDF
正文语种 eng
中图分类临床医学;
关键词
Cancer of Prostate; Prevention; overview; proven venom; description;

机译：前列腺癌;预防;概述;证明毒液;描述;

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专利

1. Delivering prostate cancer prevention messages to the public: How the National Cancer Institute (NCI) effectively spread the word about the Prostate Cancer Prevention Trial (PCPT) results. [J] . Croker KS, Ryan A, Morzenti T, Urologic oncology . 2004,第4期

机译：向公众传达前列腺癌预防信息：美国国家癌症研究所（NCI）如何有效传播有关前列腺癌预防试验（PCPT）结果的信息。
2. Prostate cancer risk prediction using the novel versions of the European Randomised Study for Screening of Prostate Cancer (ERSPC) and Prostate Cancer Prevention Trial (PCPT) risk calculators: independent validation and comparison in a contemporary European cohort [J] . Poyet Cedric, Nieboer Daan, Bhindi Bimal, BJU international . 2016,第3期

机译：使用《欧洲前列腺癌筛查随机研究（ERSPC）和前列腺癌预防试验（PCPT）风险计算器》的新版本进行的前列腺癌风险预测：在当代欧洲队列中的独立验证和比较
3. European Randomised Study of Screening for Prostate Cancer (ERSPC) risk calculators significantly outperform the Prostate Cancer Prevention Trial (PCPT) 2.0 in the prediction of prostate cancer: a multi-institutional study [J] . Foley Robert W., Maweni Robert M., Gorman Laura, BJU international . 2016,第5期

机译：一项多机构研究，欧洲前列腺癌筛查随机研究（ERSPC）风险计算器在前列腺癌的预测方面显着优于前列腺癌预防试验（PCPT）2.0
4. Clinical Models for Testing Chemopreventative Agents in Prostate Cancer and Overview of SELECT: The Selenium and Vitamin E Cancer Prevention Trial [C] . Eric A. Klein International Society of Cancer Chemoprevention . 2003

机译：用于测试前列腺癌中化学预防剂的临床模型及选择：硒和维生素E癌预防试验
5. Alpha-methylacyl-CoA racemase: A candidate gene for prostate cancer and advanced distal colorectal adenomas in the prostate, lung, colorectal, and ovarian cancer screening trial. [D] . Daugherty, Sarah. 2007

机译：α-甲基酰基辅酶A消旋酶：在前列腺癌，肺癌，结肠直肠癌和卵巢癌筛查试验中，前列腺癌和晚期远端结肠直肠腺瘤的候选基因。
6. Selective Detection of Histologically-Aggressive Prostate Cancer: an Early Detection Research Network (EDRN) Prediction Model to Reduce Unnecessary Prostate Biopsies with Validation in the Prostate Cancer Prevention Trial (PCPT) [O] . Stephen B. Williams, Simpa Salami, Meredith M. Regan, -1

机译：选择性检测组织学侵袭性前列腺癌：早期检测研究网络（EDRN）预测模型以减少不必要的前列腺活检在前列腺癌预防试验中验证（PCPT）
7. Inflammation in benign prostate tissue and prostate cancer in the finasteride arm of the Prostate Cancer Prevention Trial [O] . Murtola, Teemu J, Gurel, Bora, Umbehr, Martin, 2016

机译：前列腺癌预防试验的非那雄胺组中良性前列腺组织和前列腺癌的炎症

Implementation of the Prostate Cancer Prevention Trial (PCPT).

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