The projected effectiveness of Clostridium difficile vaccination as part of an integrated infection control strategy

van Kleef Esther; Deeny Sarah R.; Jit Mark; Cookson Barry; Goldenberg Simon D.; Edmunds W. John; Robotham Julie V.

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The projected effectiveness of Clostridium difficile vaccination as part of an integrated infection control strategy

机译：艰难梭菌疫苗接种作为综合感染控制策略的一部分的预期效果

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Background: Early clinical trials of a Clostridium difficile toxoid vaccine show efficacy in preventing C difficile infection (CDI). The optimal patient group to target for vaccination programmes remains unexplored. This study performed a model-based evaluation of the effectiveness of different CDI vaccination strategies, within the context of existing infection prevention and control strategies such as antimicrobial stewardship.

机译：背景：艰难梭菌类毒素疫苗的早期临床试验显示出预防艰难梭菌感染（CDI）的功效。尚未制定针对疫苗接种计划的最佳患者群体。这项研究在现有的感染预防和控制策略（如抗菌管理）的背景下，对不同CDI疫苗接种策略的有效性进行了基于模型的评估。

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《Vaccine》 |2016年第46期|共9页
作者
van Kleef Esther; Deeny Sarah R.; Jit Mark; Cookson Barry; Goldenberg Simon D.; Edmunds W. John; Robotham Julie V.;
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正文语种 eng
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关键词
Clostridium difficile; Vaccination; Mathematical modelling;

机译：艰难梭菌;疫苗接种;数学模型;

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专利

1. The projected effectiveness of Clostridium difficile vaccination as part of an integrated infection control strategy [J] . van Kleef Esther, Deeny Sarah R., Jit Mark, Vaccine . 2016,第46期

机译：艰难梭菌疫苗接种作为综合感染控制策略的一部分的预期效果
2. Effectiveness of targeted enhanced terminal room disinfection on hospital-wide acquisition and infection with multidrug-resistant organisms and Clostridium difficile: a secondary analysis of a multicentre cluster randomised controlled trial with crossover design (BETR Disinfection) [J] . Anderson Deverick J., Moehring Rebekah W., Weber David J., Nature reviews Cancer . 2018,第8期

机译：靶向增强终端室消毒对多级耐生物体和梭菌性梭菌性和感染的有效性：用交叉设计（Betr消毒）的多期间随机对照试验的二次分析
3. Effectiveness of targeted enhanced terminal room disinfection on hospital-wide acquisition and infection with multidrug-resistant organisms and Clostridium difficile: a secondary analysis of a multicentre cluster randomised controlled trial with crossover design (BETR Disinfection) [J] . Anderson Deverick J., Moehring Rebekah W., Weber David J., The Lancet infectious diseases . 2018,第8期

机译：靶向增强末端室消毒对多药物和梭菌梭菌的综合性收购和感染的有效性：交叉设计的多期间随机对照试验的二次分析（Betr消毒）
4. CREST - Risk Prediction for Clostridium Difficile Infection Using Multimodal Data Mining [C] . Cansu Sen, Thomas Hartvigsen, Elke Rundensteiner, European conference on machine learning and principles and practice of knowledge discovery in databases . 2017

机译：CREST-使用多模式数据挖掘的艰难梭菌感染风险预测
5. A Quality Improvement Project to Reduce the Incidence of Clostridium difficile Infection through Implementation of Evidence-Based Terminal Clean Procedures [D] . Cook, Tamara 2017

机译：一个质量改进项目，通过实施基于证据的终末清洁程序来减少艰难梭菌感染的发生
6. Effectiveness of targeted enhanced terminal room disinfection on hospital-wide acquisition and infection with multidrug-resistant organisms and Clostridium difficile: a secondary analysis of a multicentre cluster randomised controlled trial with crossover design (BETR Disinfection) [O] . Deverick J Anderson, Rebekah W Moehring, David J Weber, -1

机译：有针对性的强化终末室消毒对全院耐药菌和艰难梭菌的全院采集和感染的有效性：采用交叉设计（BETR消毒）的多中心集群随机对照试验的二次分析
7. Faculty Opinions recommendation of Effectiveness of targeted enhanced terminal room disinfection on hospital-wide acquisition and infection with multidrug-resistant organisms and Clostridium difficile: a secondary analysis of a multicentre cluster randomised controlled trial with crossover design (BETR Disinfection). [O] . Pranavi Sreeramoju 2019

机译：教师意见拟议有针对性增强末端室消毒有效性的建议对耐多种抗性生物和梭菌差异的医院采集和感染：具有交叉设计的多期间随机对照试验的二次分析（Betr消毒）。

The projected effectiveness of Clostridium difficile vaccination as part of an integrated infection control strategy

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