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Preparation and degradation of PLA/chitosan composite materials

机译:PLA /壳聚糖复合材料的制备与降解

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摘要

As scaffold material, poly(lactic acid) (PLA) has several obvious weaknesses, such as fast biodegradation, acidic degradation product, and hydrophobicity. To solve these problems, a series of PLA/chitosan composite materials was prepared in this study. SEC observation, porosity tests and contact angle measurements showed that the materials were hydrophilic and had appropriate porosity and structure, which were favorable to the cell growth. Degrading tests in vitro indicated that the degrading speeds of the materials were slower than that of PLA, and the materials could keep adjacently litmusless, certain shape and mechanical properties. (C) 2003 Wiley Periodicals, Inc. [References: 6]
机译:作为支架材料,聚乳酸(PLA)有几个明显的弱点,例如快速生物降解,酸性降解产物和疏水性。为了解决这些问题,本研究制备了一系列PLA /壳聚糖复合材料。 SEC观察,孔隙率测试和接触角测量表明,该材料是亲水性的并且具有适当的孔隙率和结构,这有利于细胞生长。体外降解试验表明,该材料的降解速度比PLA慢,并且可以保持相邻的无石蕊,一定的形状和机械性能。 (C)2003 Wiley Periodicals,Inc. [参考:6]

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