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首页> 外文期刊>Journal of Applied Polymer Science >Deposition of NonFouling Plasma Polymers to a Thermoplastic Silicone Elastomer for Microfluidic and Biomedical Applications
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Deposition of NonFouling Plasma Polymers to a Thermoplastic Silicone Elastomer for Microfluidic and Biomedical Applications

机译：将不结垢的等离子聚合物沉积到热塑性硅弹性体上，用于微流控和生物医学应用

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摘要

Plasma polymerization is used for the modification and control of surface properties of a highly transparent, thermoplastic elastomeric silicone copolymer, GENIOMER? 80 (G80). PEG-like diglyme plasma polymer films were deposited with ether retentions varying between 20% and 70% as measured by X-ray photoelectron spectroscopy analysis which did not affect the transparency of the substrate. Films with ether retentions of greater than 70% inhibit protein binding (bovine serum albumin and fibrinogen) and cell proliferation. A short oxygen plasma pretreatment enhances the adhesion and stability of the film as shown by protein binding and cell adhesion experiments. The transparency of the material and the stability of the coating makes this material a versatile bulk material for technical (e.g., lab-on-a-chip) and biomedical (e.g., intraocular lens) applications. The G80/plasma polymer composite is stable against vigorous washing and storage over 5 months and, therefore, offers an attractive alternative to poly(dimethylsiloxane).
机译：等离子体聚合用于改性和控制高度透明的热塑性弹性体有机硅共聚物GENIOMER®。 80（G80）。通过X射线光电子能谱分析法测得，PEG样二甘醇二甲醚等离子聚合物膜沉积的醚保留量在20％至70％之间变化，这不影响基材的透明度。醚保留率大于70％的薄膜会抑制蛋白质结合（牛血清白蛋白和纤维蛋白原）和细胞增殖。短暂的氧等离子体预处理可增强膜的粘附力和稳定性，如蛋白结合和细胞粘附实验所示。该材料的透明性和涂层的稳定性使该材料成为用于技术（例如，芯片实验室）和生物医学（例如，人工晶状体）应用的通用块状材料。 G80 /等离子聚合物复合材料在超过5个月的时间里仍能稳定抵抗剧烈洗涤和储存，因此，它是聚二甲基硅氧烷的有吸引力的替代品。

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