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首页> 外文期刊>Journal of Applied Polymer Science >Synthesis and Properties of a Polymerizable Quaternary Ammonium Salt
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Synthesis and Properties of a Polymerizable Quaternary Ammonium Salt

机译：可聚合季铵盐的合成与性能

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摘要

Novel polymerizable monomer N,N-dimethyl-2-[(2-methylacryloyl)oxy] ethanaminium 5-carboxy-2,4-bis benzoate (DMAEMA-PMDPM salt) was synthesized by acid-alkali neutralizing reaction and was proved to be successful by Fourier transform infrared spectroscopy. The antibacterial activity and cytotoxicity of monomer were assessed by determination of the minimal inhibitory concentration and minimal bactericidal concentration, time-kill study and methyltetrazolium test assay. Polymerizable efficiency was determined by measurement of degree of conversion. The results indicated that DMAEMA-PMDPM salt which is a kind of liquid polymerizable has some antimicrobial activity and similar cytotoxicity to common dental resin monomers. The new monomer also has a high polymerizable ability. Therefore it might have a great potential to prepare antimicrobial coatings on denture base and soft lining materials, as well as some biomedical applications. VC 2014 Wiley Periodicals, Inc. J. Appl. Polym. Sci. 2014, 131, 41002.
机译：通过酸-碱中和反应合成了新型可聚合单体N，N-二甲基-2-[（（2-甲基丙烯酰基）氧基]乙铵5-羧基-2,4-双苯甲酸酯（DMAEMA-PMDPM盐），并证明是成功的通过傅立叶变换红外光谱。通过确定最小抑菌浓度和最小杀菌浓度，时间杀灭研究和甲基四唑鎓试验测定法评估单体的抗菌活性和细胞毒性。通过测量转化率来确定可聚合效率。结果表明，DMAEMA-PMDPM盐是一种可液态聚合的盐，与普通的牙科树脂单体相比，具有一定的抗菌活性和相似的细胞毒性。新单体还具有高聚合能力。因此，在义齿基托和软衬材料上制备抗菌涂层可能具有巨大的潜力，以及一些生物医学应用。 VC 2014 Wiley Periodicals，Inc. J. Appl。 Polym。科学2014，131，41002。

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