In this second of two articles, we explore the range of common smaller specimens that present to the ophthalmic histopathology laboratory. Some of these specimens are quite small and difficult to handle, with a proven rate of loss during processing. This article contains techniques to overcome such difficulties. The full spectrum of biopsy material is covered, from full-thickness eyelid pentagonal resections, through to aspirations of intraocular tumours and handling tiny epiretinal membranes.
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