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Acute effects of air pollution on type II diabetes mellitus hospitalization in Shijiazhuang, China

机译:空气污染对西家庄,中国石家庄II型糖尿病住院治疗的急性作用

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摘要

Air pollution has been considered as an important contributor to diabetes development. However, the evidence is fewer in developing countries where air pollution concentrations were much higher. In this study, we conduct a time-series study to investigate the acute adverse effect of six air pollutants on type II diabetes mellitus (T2DM) hospitalization in Shijiazhuang, China. An over-dispersed passion generalized addictive model adjusted for weather conditions, day of the week, and long-term and seasonal trends was used. Finally, a 10-μg/m_(3)increase of fine particulate matter (PM~(2.5)), inhalable particulate matter (PM~(10)), sulfur dioxide (SO~(2)), nitrogen dioxide (NO~(2)), and carbon monoxide (CO) corresponded to 0.53% (95% confidence interval?=?0.22–0.83), 0.32% (95% CI?=?0.10–0.55), 0.55% (95% CI?=?0.04–1.07), 1.27% (95% CI?=?0.33–2.22), and 0.04% (95% CI?=?0.02–0.06) increment of T2DM hospitalization, respectively. The effects of PM~(2.5), PM~(10), and CO were robust when adjusted for co-pollutants. The associations appeared to be a little stronger in the cool season than in the warm season. And stronger associations were found in male and elderly (≥?65?years) than in female and younger people (35–65?years). Our results contribute to the limited data in the scientific literature on acute effects of air pollution on type II diabetes mellitus in developing countries. Main findings : This is the first adverse effect evidence of air pollution on T2DM in Shijiazhuang, a severely polluted city in China. Males were more vulnerable than females in severe pollution.
机译:空气污染被认为是糖尿病发展的重要贡献者。但是,在空气污染浓度要高得多的发展中国家,证据较少。在这项研究中,我们进行了一项时间序列的研究,探讨了六种空气污染物对Shijijiazhuang型糖尿病(T2DM)住院的急性不利影响。使用过度分散的激情广泛性上瘾模型,用于天气条件,一周中的一天,以及长期和季节性趋势。最后,10μg/ m_(3)细颗粒物质的增加(PM〜(2.5)),可吸入颗粒物质(PM〜(10)),二氧化硫(SO〜(2)),二氧化氮(不〜 (2)),一氧化碳(CO)对应0.53%(95%置信区间α=→0.22-0.83),0.32%(95%CI = = 0.10-0.55),0.55%(95%CI?= ?0.04-1.07),1.27%(95%CI?= 0.33-2.22),分别为0.04%(95%CI?= 0.02-0.06)T2DM住院的增量。 PM〜(2.5),PM〜(10)和CO的效果在调整用于共污染物时具有稳健性。协会在酷季节似乎比温暖季节更强大。在雄性和老年人(≥65?年)中发现了更强的协会,而不是女性和年轻人(35-65岁)。我们的成果有助于对发展中国家II型糖尿病的空气污染急性影响的科学文献有限。主要发现:这是石家庄T2DM在中国污染严重污染城市的T2DM空气污染的第一个不利影响证据。男性比严重污染的女性更脆弱。

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