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首页> 外文期刊>Surgical Endoscopy >Outcome of peroral endoscopic myotomy in children with achalasia
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Outcome of peroral endoscopic myotomy in children with achalasia

机译：贲门划分的儿童情境镜肌动术的结果

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摘要

Background and aims Achalasia cardia is rare in children and optimum endoscopic management options are not well known. Peroral endoscopic myotomy (POEM) is a novel treatment modality for achalasia with excellent results in adult patients. The long-term outcomes of POEM are not well known in children. In this study, we aim to evaluate the outcome of POEM in children with idiopathic achalasia. Methods We analyzed the data of children (<= 18 years) diagnosed with achalasia from September 2013 to January 2018. Technical success, clinical success, and adverse events were assessed. Post-POEM, gastroesophageal reflux (GER) was assessed with 24-h pH-impedance study and esophagogastroduodenoscopy. Results A total of 44 children (boys-23, girls-21) with mean age of 14.5 +/- 3.41 years (4-18) were diagnosed with achalasia during the study period. Of these, 43 children underwent POEM. The subtypes of achalasia according to Chicago classification were type I-11, type II-29, type III-2, and unclassified-2. Eighteen children (40.9%) had history of prior treatment. POEM was successfully performed in 43 children (technical success-97.72%). Intra-operative adverse events occurred in 11 (25.6%) children including retroperitoneal CO2 (7), capnoperitoneum (3), and mucosal injury (1). Clinical success at 1, 2, 3, and 4 years' follow-up was 92.8%, 94.4%, 92.3%, and 83.3%, respectively. Erosive esophagitis was detected in 55% (11/20) children. On 24-h pH study, GER was detected in 53.8% (7/13) children. Conclusion POEM is a safe, effective, and durable treatment for achalasia in children. However, GER is a potential concern and should be evaluated in prospective studies before adopting POEM for the management of achalasia in children.
机译：背景和AIMS Achalasia Cardia在儿童中罕见，并且最佳内窥镜管理选择并不众所周知。 Peroral内镜下肌动术（POEM）是一种新的治疗方式，适用于成年患者的优异成果。诗歌的长期结果在儿童中不为人知。在这项研究中，我们的目标是评估特发性贲门刺激儿童诗的结果。方法分析了2013年9月至2018年1月诊断患儿童的数据（<= 18岁）的数据。评估了技术成功，临床成功和不良事件。诗歌后，用24-H pH阻抗研究和食噬杆菌的研究和食噬杆菌研究评估胃食管反流（GER）。结果共有44名儿童（男孩-23，女孩-21），平均年龄为14.5 +/- 3.41岁（4-18），在研究期间被诊断患有疗法障碍。其中，43名儿童接受了诗歌。根据芝加哥分类的肺活结亚型是I-11型，II-29型，III型，和未分类-2。十八个孩子（40.9％）有先前治疗的历史。诗歌于43名儿童成功进行（技术成功-97.72％）。在11（25.6％）的儿童中发生术中术中不良事件，包括腹膜腹膜CO2（7），章萘啶（3）和粘膜损伤（1）。 1,2,3和4年后续的临床成功分别为92.8％，94.4％，92.3％和83.3％。在55％（11/20）儿童中检测到腐蚀性食管炎。在24小时pH学习中，在53.8％（7/13）儿童中检测到GER。结论POEM是儿童贲门划分的安全，有效和耐用的治疗方法。然而，GER是一个潜在的疑虑，并且应该在采用诗歌中的前瞻性研究中进行评估，以便在儿童贲门划分症的管理。

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  • 来源
    《Surgical Endoscopy》 |2019年第11期|共9页
  • 作者

    Nabi Zaheer; Ramchandani Mohan; Chavan Radhika; Darisetty Santosh; Kalapala Rakesh; Shava Upender; Tandan Manu; Kotla Rama; Reddy D. Nageshwar;

  • 作者单位

    Asian Inst Gastroenterol 6-3-661 Somajiguda Hyderabad 500082 India;

    Asian Inst Gastroenterol 6-3-661 Somajiguda Hyderabad 500082 India;

    Asian Inst Gastroenterol 6-3-661 Somajiguda Hyderabad 500082 India;

    Asian Inst Gastroenterol 6-3-661 Somajiguda Hyderabad 500082 India;

    Asian Inst Gastroenterol 6-3-661 Somajiguda Hyderabad 500082 India;

    Asian Inst Gastroenterol 6-3-661 Somajiguda Hyderabad 500082 India;

    Asian Inst Gastroenterol 6-3-661 Somajiguda Hyderabad 500082 India;

    Asian Inst Gastroenterol 6-3-661 Somajiguda Hyderabad 500082 India;

    Asian Inst Gastroenterol 6-3-661 Somajiguda Hyderabad 500082 India;

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  • 原文格式 PDF
  • 正文语种 eng
  • 中图分类 诊断学;
  • 关键词

    Achalasia; Child; Endoscopy; Myotomy;

    机译：achalasia;孩子;内窥镜检查;myotomy;

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