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首页> 外文期刊>Pediatrics: Official Publication of the American Academy of Pediatrics >Factors Associated With Rotavirus Vaccine Coverage
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Factors Associated With Rotavirus Vaccine Coverage

机译：与轮状病毒疫苗覆盖有关的因素

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BACKGROUND: Rotavirus vaccines (RVVs) were included in the US immunization program in 2006 and are coadministered with the diphtheria-tetanus-acellular pertussis (DTaP) vaccine, yet their coverage lags behind DTaP. We assessed timing, initiation, and completion of the RVV series among children enrolled in active gastroenteritis surveillance at 7 US medical institutions during 2014-2016. METHODS: We compared coverage and timing of each vaccine series and analyzed characteristics associated with RVV initiation and completion. We report odds ratios (ORs) and 95% confidence intervals (CIs) from multivariable logistic regression models. RESULTS: We enrolled 10 603 children. In 2015, = 1 dose coverage was 91% for RVV and 97% for DTaP. Seven percent of children received their first DTaP vaccine at age = 15 weeks versus 4% for RVV (P = .001). Recent birth years (2013-2016) were associated with higher odds of RVV initiation (OR = 5.72; 95% CI 4.43-7.39), whereas preterm birth (OR = 0.32; 95% CI 0.24-0.41), older age at DTaP initiation (OR 0.85; 95% CI 0.80-0.91), income between $50 000 and $100 000 (OR = 0.56; 95% CI 0.40-0.78), and higher maternal education (OR = 0.52; 95% CI 0.36-0.74) were associated with lower odds. Once RVV was initiated, recent birth years (2013-2016; OR = 1.57 [95% CI 1.32-1.88]) and higher maternal education (OR = 1.31; 95% CI 1.07-1.60) were associated with higher odds of RVV completion, whereas preterm birth (OR = 0.76; 95% CI 0.62-0.94), African American race (OR = 0.82; 95% CI 0.70-0.97) and public or no insurance (OR = 0.75; 95% CI 0.60-0.93) were associated with lower odds. Regional differences existed. CONCLUSIONS: RVV coverage remains lower than that for the DTaP vaccine. Timely DTaP administration may help improve RVV coverage.
机译：背景：轮状病毒疫苗（RVVs）被列入2006年美国免疫规划，并与白喉 - 破伤风 - 百日咳（的DTaP）疫苗，但接种DTaP背后的覆盖面滞后联合给药。我们评估时机，启动和RVV儿童系列中2014至2016年在积极胃肠炎监控就读于美国7个医疗机构完成。方法：我们比较了各系列疫苗的覆盖范围和时间，并分析了RVV启动和完成相关的特征。我们报告比值比（OR）和多变量回归模型95％可信区间（CI）。结果：我们招收10名603儿童。在2015年，＆GT; = 1剂量覆盖率为91 RVV％和的DTaP 97％。孩子的百分之七首次获得的DTaP疫苗在年龄＆GT; = 15周与用于RVV 4％（P＆LT; = 0.001）。 （; 95％CI 4.43-7.39 OR = 5.72），而早产（OR = 0.32; 95％CI 0.24-0.41），年龄在的DTaP引发最近出生年（2013至2016年）与RVV引发的高赔率相关（OR 0.85; 95％CI 0.80-0.91），收入50 000 $ 100 $ 000（OR = 0.56; 95％CI 0.40-0.78）之间，和更高的母体教育（OR = 0.52; 95％CI 0.36-0.74）中相关联的较低的赔率。一旦RVV已启动，近几年出生（2013-2016; OR = 1.57 [95％CI 1.32-1.88]）和更高母亲受教育程度（OR = 1.31; 95％CI 1.07-1.60）与RVV完成的可能性较高有关，而早产（OR = 0.76; 95％CI 0.62-0.94），非裔美国人的种族（OR = 0.82; 95％CI 0.70-0.97）和公共或没有保险（OR = 0.75; 95％CI 0.60-0.93）的相关较低的赔率。地区差异的存在。结论：RVV覆盖率仍然高于对的DTaP疫苗降低。及时的DTaP管理可以帮助改善RVV覆盖。

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