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Pathology of the liver

机译:肝脏病理

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摘要

Traditional anatomic pathology studies and molecular investigations both contributed to the breadth of current information in the field of liver pathology this year. Techniques such as reverse transcription polymerase chain reaction can identify recurrence of hepatitis C virus infection in the liver as early as 5 days after transplantation. Chronic rejection after transplantation may be characterized not only by ductopenia but also by loss of portal tract hepatic artery branches. There are many diseases of small bile ducts in adults, and idiopathic adulthood ductopenia has been identified in extended family members. Adverse reactions to drugs may precipitate their removal from the pharmacopoeia, such as the many cases reported of severe bridging and submassive necrosis due to troglitazone (a thiazolidinedione antidiabetic agent). Several publications highlighted the association of hepatitis C virus infection with lymphoproliferative diseases and, newly, with cholangiocarcinoma.
机译:传统的解剖病理学研究和分子研究都为今年肝脏病理学领域的最新信息做出了贡献。逆转录聚合酶链反应等技术可在移植后5天之内识别出丙型肝炎病毒感染在肝脏中的复发。移植后的慢性排斥反应不仅可以表现为胆管减少,还可以表现为门静脉肝动脉分支的丢失。成人有许多胆小管疾病,在大家庭中已发现特发性成年性胆管减少症。对药物的不良反应可能促使其从药典中清除,例如许多报道由于曲格列酮(噻唑烷二酮类抗糖尿病药)导致严重桥接和亚大面积坏死的病例。一些出版物强调了丙型肝炎病毒感染与淋巴增生性疾病以及新近与胆管癌的关系。

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