...
  • 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>The Journal of pediatrics >Maternal obesity, gestational weight gain, and offspring adiposity: The exploring perinatal outcomes among children study
【24h】

Maternal obesity, gestational weight gain, and offspring adiposity: The exploring perinatal outcomes among children study

机译：孕产妇肥胖，妊娠重量，和后代肥胖：探索儿童研究中的围产期结果

获取原文
获取原文并翻译 | 示例
           
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

Objective To determine whether adequate vs excessive gestational weight gain (GWG) attenuated the association between maternal obesity and offspring outcomes. Study design Data from 313 mother-child pairs participating in the Exploring Perinatal Outcomes among Children study were used to test this hypothesis. Maternal prepregnancy body mass index (BMI) and weight measures throughout pregnancy were abstracted from electronic medical records. GWG was categorized according to the 2009 Institute of Medicine criteria as adequate or excessive. Offspring outcomes were obtained at a research visit (average age 10.4 years) and included BMI, waist circumference (WC), subcutaneous adipose tissue (SAT) and visceral adipose tissue, high-density lipoprotein cholesterol, and triglyceride levels. Results More overweight/obese mothers exceeded the Institute of Medicine GWG recommendations (68%) compared with normal-weight women (50%) (P .01). Maternal prepregnancy BMI was associated with worse childhood outcomes, particularly among offspring of mothers with excessive GWG (increased BMI [20.34 vs 17.80 kg/m2], WC [69.23 vs 62.83 cm], SAT [149.30 vs 90.47 cm2], visceral adipose tissue [24.11 vs 17.55 cm2], and homeostatic model assessment [52.52 vs 36.69], all P .001). The effect of maternal prepregnancy BMI on several childhood outcomes was attenuated for offspring of mothers with adequate vs excessive GWG (P .05 for the interaction between maternal BMI and GWG status on childhood BMI, WC, SAT, and high-density lipoprotein cholesterol). Conclusion Our findings lend support for pregnancy interventions aiming at controlling GWG to prevent childhood obesity.
机译：目的判断是否有足够的妊娠权重增益（GWG）抑制了母体肥胖和后代结果之间的关联。研究设计数据来自参与儿童研究中的探索围产期成果的313母婴对进行测试。孕产妇预妊娠体重指数（BMI）和妊娠的重量措施从电子医疗记录中抽象出来。根据2009年医学标准研究所适当或过度分类，GWG分类。在研究访问（平均年龄10.4岁）中获得了后代结果，包括BMI，腰围（WC），皮下脂肪组织（SAT）和内脏脂肪组织，高密度脂蛋白胆固醇和甘油三酯水平。结果超重/肥胖母亲超过了医学研究所GWG建议（68％）与正常重量（50％）（P <.01）。母体预妊娠BMI与较差的儿童结果有关，特别是母亲的后代，具有过量的GWG（BMI增加[20.34 Vs17.80kg / M2]，WC [69.23 Vs 62.83cm]，坐落[149.30 Vs 90.47cm2]，内脏脂肪组织[ 24.11 Vs 17.55 cm2]和稳态模型评估[52.52 Vs 36.69]，所有P＆ .001）。母体预妊娠BMI对若干儿童结果的影响衰减用于母亲的后代，具有足够的GWG过量的GWG（P <.05用于儿童BMI，WC，SAT和高密度脂蛋白胆固醇胆固醇的母体BMI和GWG状态之间的相互作用。 ）。结论我们的调查结果借助旨在控制GWG以防止儿童肥胖的妊娠干预措施。

著录项

  • 来源
    《The Journal of pediatrics》 |2014年第3期|共7页
  • 作者

    KaarJ.L.; CrumeT.; BrintonJ.T.; BischoffK.J.; McDuffieR.; DabeleaD.;

  • 作者单位

    Department of Pediatrics University of Colorado School of Medicine Aurora CO 80045 United States;

    Department of Epidemiology Colorado School of Public Health University of Colorado Denver Denver;

    Department of Biostatistics and Informatics Colorado School of Public Health University of;

    Institute for Health Research Kaiser Permanente of Colorado Denver CO United States;

    Department of Perinatology Kaiser Permanente of Colorado Denver CO United States;

    Department of Epidemiology Colorado School of Public Health University of Colorado Denver Denver;

  • 收录信息
  • 原文格式 PDF
  • 正文语种 eng
  • 中图分类 儿科学;
  • 关键词

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号