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Small intestinal motility.

机译:小肠蠕动。

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摘要

PURPOSE OF REVIEW: In the past year, many studies were published in which new and relevant information on small intestinal motility in humans and laboratory animals was obtained. RECENT FINDINGS: Although the reported findings are heterogeneous, some themes appear to be particularly interesting and novel. Among these is the association between disordered small intestinal motility and bacterial overgrowth of the small intestine. Studies in patients with portal hypertension, in patients with chronic renal failure, and in a rat model of experimental acute pancreatitis all point in the same direction. Another topic of particular interest is the relation between duodenal motility and glucose absorption; propagated duodenal pressure wave sequences are positively related to glucose absorption. Finally, many studies addressed the mechanisms involved in the regulation of interdigestive and postprandial small intestinal motility. These confirmed the key role of cholecystokinin and provided new information on therole of orexin A and leptin. SUMMARY: The new information on intestinal motility gathered in the past year provides a greater insight in the pathophysiology of a number of diseases and will stimulate further studies in laboratory animals and in human subjects.
机译:审查目的:在过去的一年中,发表了许多研究,这些研究获得了有关人类和实验动物小肠蠕动的新的相关信息。最近的发现:尽管报道的发现是不同的,但某些主题似乎特别有趣和新颖。其中包括小肠蠕动紊乱与小肠细菌过度生长之间的关联。对门静脉高压症患者,慢性肾功能衰竭患者和实验性急性胰腺炎大鼠模型的研究都指向同一方向。另一个特别令人感兴趣的话题是十二指肠蠕动与葡萄糖吸收之间的关系。传播的十二指肠压力波序列与葡萄糖吸收呈正相关。最后,许多研究探讨了消化间和餐后小肠运动的调节机制。这些证实了胆囊收缩素的关键作用,并提供了有关orexin A和leptin理论的新信息。摘要:过去一年收集的有关肠道运动的新信息为许多疾病的病理生理学提供了更深刻的见解,并将刺激对实验动物和人类受试者的进一步研究。

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