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首页> 外文期刊>Current opinion in lipidology >Diet and nonalcoholic fatty liver disease.
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Diet and nonalcoholic fatty liver disease.

机译：饮食和非酒精性脂肪肝疾病。

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PURPOSE OF REVIEW: Nonalcoholic fatty liver disease is a common and serious form of chronic liver disease. It is characterized by lipid accumulation in the liver and is associated with all aspects - and may even be an initiating factor - of the metabolic syndrome. The purpose of this review is to summarize recent findings from human studies on dietary effects on hepatic lipid accumulation. RECENT FINDINGS: Epidemiological studies did not give consistent results. From intervention studies there is evidence to support a role for weight loss. Some studies have also suggested that decreasing total fat intake and increasing the intake of fish oils may be beneficial in the treatment of nonalcoholic steatohepatitis. SUMMARY: Only a few studies have focused on dietary effects on hepatic lipid accumulation. So far, there is only evidence to support a role for weight loss. Decreasing total fat intake and increasing the intake of fish oils may also be beneficial, but these conclusions are based on a limited number of studies, which sometimes lacked a proper control group. Also, other nutrients have not been studied in detail. Therefore, there is an urgent need for evidence-based dietary guidelines to prevent or even to treat nonalcoholic fatty liver disease.
机译：审查目的：非酒精性脂肪肝是慢性肝病的常见和严重形式。它的特征是脂质在肝脏中的蓄积，并与代谢综合征的所有方面相关，甚至可能是其引发因素。这篇综述的目的是总结关于饮食对肝脂质积累的人体研究的最新发现。最近的发现：流行病学研究没有给出一致的结果。从干预研究中，有证据支持减肥作用。一些研究还表明，减少总脂肪摄入量和增加鱼油摄入量可能对治疗非酒精性脂肪性肝炎有益。摘要：只有很少的研究集中在饮食对肝脂质蓄积的影响。到目前为止，只有证据支持减肥作用。减少总脂肪摄入量和增加鱼油摄入量也可能是有益的，但是这些结论基于有限的研究，有时缺乏适当的对照组。另外，尚未详细研究其他营养素。因此，迫切需要基于证据的饮食指南，以预防甚至治疗非酒精性脂肪肝。

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