Therapy and clinical trials.

Devendra GP; Krasuski RA

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Therapy and clinical trials.

机译：治疗和临床试验。

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Early 2010 was notable for the publication of two studies examining adjunctive therapy to statins in patients at high cardiovascular risk. Despite significant risk reduction with statins, evidence suggests considerable, residual cardiovascular risk in statin-treated patients [1-3]. In light of this, investigators of both the Action to Control Cardiovascular Risk in Diabetes Lipid Trial (ACCORD Lipid) [4**] and the Arterial Biology for the Investigation of the Treatment Effects of Reducing Cholesterol: HDL and LDL Treatment Strategies in Atherosclerosis study (ARBITER 6-HALTS) [5**] explored the efficacy of add-on therapy.

机译：2010年初，发表了两项研究，研究心血管高危患者对他汀类药物的辅助治疗。尽管他汀类药物可显着降低风险，但证据表明，他汀类药物治疗的患者仍有相当大的残余心血管风险[1-3]。有鉴于此，研究者对控制糖尿病脂质试验（ACCORD脂质）中心血管风险的作用[4 **]和研究降低胆固醇的治疗效果的动脉生物学研究：动脉粥样硬化研究中的HDL和LDL治疗策略（第6栏-HALTS）[5 **]探索了附加疗法的功效。

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《Current opinion in lipidology》 |2010年第5期|共2页
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Devendra GP; Krasuski RA;
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中图分类生物化学;
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1. Impact of emesis on clinical and economic outcomes of cancer therapy with highly emetogenic chemotherapy regimens: a retrospective analysis of three clinical trials. [J] . Neymark N, Crott R Supportive care in cancer: official journal of the Multinational Association of Supportive Care in Cancer . 2005,第10期

机译：呕吐对高度呕吐化疗方案的癌症治疗的临床和经济结果的影响：回顾性分析三项临床试验。
2. Impact of ultrahigh baseline PSA levels on biochemical and clinical outcomes in two Radiation Therapy Oncology Group prostate clinical trials. [J] . Rodrigues G, Bae K, Roach M, International Journal of Radiation Oncology, Biology, Physics . 2011,第2期

机译：两项放射疗法肿瘤学小组前列腺临床试验中，超高基线PSA水平对生化和临床结果的影响。
3. The Value of Observational Cohort Studies for Cancer DrugsRandomized controlled trials - the gold standard for clinical drug evaluation -can't always predict adverse events in real-world settings. For the new cancer therapies, observational cohort studies (OCSs) can help evaluate their effects in broader populations and provide valuable information for future clinical trials. [J] . DAVID R. SPIGEL Biotechnology healthcare . 2010,第2期

机译：观察性队列研究对癌症药物的价值随机对照试验-临床药物评估的金标准-不能总是预测现实世界中的不良事件。对于新的癌症疗法，观察性队列研究（OCS）可以帮助评估它们在更广泛的人群中的作用，并为将来的临床试验提供有价值的信息。
4. Artificial Blood—RBC Substitute: Research Development and Clinical Trials. [C] . (Missing) 11th Regional Western Pacific Congress of International Society of Blood Transfusion Nov, 2001 Shanghai . 2001

机译：人造血-RBC替代品：研究与开发和临床试验。
5. Statistical methods for biomarker threshold models in clinical trials. [D] . Gavanji, Parisa. 2017

机译：临床试验中生物标志物阈值模型的统计方法。
6. Informed consent in clinical trials. ... of the principles of clinical trials. [O] . H Thornton 1993

机译：临床试验中知情同意。 ...临床试验的原理。
7. Informed consent in clinical trials. ... of the principles of clinical trials. [O] . Thornton, H 1993

机译：临床试验中知情同意。 ...临床试验的原理。
8. Cell Therapy: Filling the Gap Between Basic Science and Clinical Trials. First International Workshop held in Rome, Italy on October 15-17, 2001 [R] . Migliaccio, A. R., Carta, C., Campisi, S. 2001

机译：细胞疗法：填补基础科学与临床试验之间的空白。第一届国际研讨会于2001年10月15日至17日在意大利罗马举行

Therapy and clinical trials.

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