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Continuous epidural administration of droperidol to prevent postoperative nausea and vomiting

机译:蜕膜施用滴注酚,以防止术后恶心和呕吐

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摘要

This randomized double-blind trial was designed to evaluate the antiemetic effect of continuous epidural analgesia with droperidol mixed with bupivacaine and buprenorphine. We studied 78 patients for abdominal gynecological surgery under general-epidural anesthesia. After recovery from anesthesia, they received epidural administration of 0.25% bupivacaine 40 ml and buprenorphine 0.4 mg with or without droperidol 2.5-5.0 mg at a rate of 2 ml.h-1 for 24 hours. The addition of droperidol 5.0 mg led to serious undesirable effects. Droperidol 2.5 mg, however, showed not only significant antiemetic effect without any adverse action, but also the reduction of rescue analgesics. We conclude that the addition of a small dose of droperidol to epidural analgesics reduces the incidence of postoperative emesis and the requirement of rescue analgesics.
机译:这种随机的双盲试验旨在评估连续硬膜外镇痛与与Bupivacaine和Buprenorphine混合的脱甲酰苯甲酸的抑制作用。 在一般硬膜外麻醉下,我们研究了78名腹部妇科手术患者。 在麻醉中恢复后,它们收到0.25%Bupivacaine 40mL和Buprenorphine 0.4mg的硬膜外施用,其中没有滴注液2.5-5.0mg,以2mL-1的速率进行24小时。 添加Droperidol 5.0 mg导致严重的不良影响。 然而,蜕膜2.5毫克没有任何不良行动的显着止吐效果,也表明了救援镇痛药的减少。 我们得出结论,添加小剂量的硬膜外镇痛药减少了术后呕吐的发生率和救援镇痛药的要求。

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