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首页> 外文期刊>Biotechnology Advances: An International Review Journal >Biomolecule-embedded metal-organic frameworks as an innovative sensing platform
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Biomolecule-embedded metal-organic frameworks as an innovative sensing platform

机译：生物分子嵌入式金属有机框架作为创新的传感平台

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摘要

Technological advancements combined with materials research have led to the generation of enormous types of novel substrates and materials for use in various biological/medical, energy, and environmental applications. Lately, the embedding of biomolecules in novel and/or advanced materials (e.g., metal-organic frameworks (MOFs), nanoparticles, hydrogels, graphene, and their hybrid composites) has become a vital research area in the construction of an innovative platform for various applications including sensors (or biosensors), biofuel cells, and bioelectronic devices. Due to the intriguing properties of MOFs (e.g., framework architecture, topology, and optical properties), they have contributed considerably to recent progresses in enzymatic catalysis, antibody-antigen interactions, or many other related approaches. Here, we aim to describe the different strategies for the design and synthesis of diverse biomolecule-embedded MOFs for various sensing (e.g., optical, electrochemical, biological, and miscellaneous) techniques. Additionally, the benefits and future prospective of MOFs-based biomolecular immobilization as an innovative sensing platform are discussed along with the evaluation on their performance to seek for further development in this emerging research area.
机译：与材料研究相结合的技术进步导致了各种类型的新型基板和用于各种生物/医学，能源和环境应用的材料。最近，在新颖和/或先进材料（例如，金属 - 有机骨架（MOF），纳米粒子，水凝胶，石墨烯及其杂种复合材料中嵌入生物分子（例如，金属 - 有机骨架（MOF），杂种复合材料）已经成为建造各种创新平台的重要研究领域包括传感器（或生物传感器），生物燃料电池和生物电子器件的应用。由于MOF的有趣特性（例如，框架架构，拓扑和光学性质），它们促进了诸如酶催化，抗体 - 抗原相互作用或许多其他相关方法中的最近进展的贡献。在这里，我们的目标是描述用于各种传感（例如光学，电化学，生物学和杂项）技术的各种生物分子嵌入式MOF的设计和合成的不同策略。此外，根据他们的绩效的评估，讨论了基于MOFS的生物分子固定作为创新传感平台的益处和未来前瞻性，以便在这一新兴研究区域寻求进一步发展的绩效。

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