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The non-invasive tear film break-up time in normal children

机译：非侵入性撕裂膜分解时间在正常儿童中

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摘要

Objective: To perform an objective evaluation of the non-invasive tear break-up time (NITBUT) and lipid layer interferometry in normal children. Methods: Children with no known ocular surface disease or anterior segment abnormality were evaluated. We excluded patients with disorders affecting lid margins or tear film composition. NITBUT and lipid layer interferometry were performed using a Keeler tearscope mounted on a slit lamp. The time from eye opening to the first distortion of the grid was noted. The average of three readings was taken as the NITBUT. Results: Thirty-six children (71 eyes) were included (mean age 7.64 years, range 2.16-15.83 years). Mean NITBUT was 21.76±4.06 s (range 14.9-30.95). This is significantly higher in comparison to recent adult studies utilising the tearscope. Twenty-four children allowed tearscope lipid layer interferometry. Eighteen demonstrated grade 1 and six demonstrated grade 2. These grades are within the normal tear film range. Conclusions: To our knowledge, this prospective study is the first to evaluate NITBUT in normal children. The results demonstrate that NITBUT is greater in children in comparison to adults. These normative data are a useful benchmark for further research into tear film instability in children.
机译：目的：在正常儿童中对非侵入性撕裂时间（NITBIT）和脂质层干涉测量进行客观评价。方法：评价含有已知眼部疾病或前段异常的儿童。我们排除了影响盖子边缘或泪膜组成的疾病的患者。使用安装在狭缝灯上的Keeler Tearscope进行NITBUT和脂质层干涉法。注意到从眼睛开口到网格的第一个失真的时间。三个读数的平均值作为NITBUT。结果：包括三十六名儿童（71只眼）（平均年龄7.64岁，范围为2.16-15.83岁）。平均值为21.76±4.06 s（范围为14.9-30.95）。与利用Tearscope的最近成人研究相比，这显着更高。二十四个儿童允许泪水脂层干涉测量。十八级展示1级和六级展示2.这些等级在正常的泪膜范围内。结论：据我们所知，这项前瞻性研究是第一个评估正常儿童的NITBUT。结果表明，与成年人相比，儿童的NITBUT更大。这些规范数据是进一步研究儿童撕裂膜不稳定的有用基准。

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  • 来源
    《British journal of ophthalmology》 |2013年第9期|共5页
  • 作者

    JonesS.M.; NischalK.K.;

  • 作者单位

    Clinical and Academic Department of Ophthalmology Great Ormond Street Hospital for Children;

    Clinical and Academic Department of Ophthalmology Great Ormond Street Hospital for Children;

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  • 正文语种 eng
  • 中图分类 眼科学;
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