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首页> 外文期刊>Canadian Veterinary Journal: La Revue Veterinaire Canadienne. >Do plasma protein:fibrinogen ratios in horses provide additional information compared with fibrinogen concentration alone?
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Do plasma protein:fibrinogen ratios in horses provide additional information compared with fibrinogen concentration alone?

机译:血浆蛋白质:与单独的纤维蛋白原浓度相比,马匹中的纤维蛋白原比提供额外的信息吗?

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摘要

The plasma proteinrfibrinogen (PP:F) ratio was introduced to aid interpretation of hyperfibrinogenemia by accounting for dehydration. However, this ratio is inconsistently assessed in practice and its clinical value remains unknown. Our objective wasto determine whether the PP:F ratio provides additional information in adult horses beyond fibrinogen concentration alone. Two databases were reviewed to identify 412 hyperfìbrinogenemic horses. Plasma proteimfibrinogen ratios were calculated and theirinterpretation compared to the fibrinogen concentration. Ratios < 15 were supportive of inflammation. Albumin and total protein concentrations were evaluated when ratios were & 15 to determine if inflammation was supported. Very good agreement (86%) wasfound on the presence of inflammation when PP:F ratios were compared to fibrinogen concentration. In 72% of cases in which PP:F ratios did not support inflammation, inflammation was considered likely based on albumin and total protein. These findings suggest that PP:F ratios do not provide additional information in horses over fibrinogen concentrations alone.
机译:引入血浆蛋白蛋白纤维蛋白原(PP:F)比以通过核算脱水来帮助解释高纤维蛋白血症。然而,这种比率在实践中不一致地评估,其临床价值仍然未知。我们的客观Wasto确定PP:F比是否提供除纤维蛋白原浓度之外的成人马中的其他信息。审查了两种数据库以鉴定412个血汗血管生殖马。与纤维蛋白原浓度相比,计算血浆蛋白纤维蛋白原比并进行诠释物。比率<15是炎症的支持性。当比率为&15以确定是否支持炎症时,评价白蛋白和总蛋白质浓度。当PP:F比率与纤维蛋白原浓度进行比较时,非常良好的一致性(86%)在炎症存在下呈现。在72%的病例中,其中PP:F比率不支持炎症,炎症被认为是基于白蛋白和总蛋白质的。这些发现表明,PP:F比率在单独的纤维蛋白原浓度上不提供马匹的其他信息。

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