Kidney development and perspectives for organ engineering

Reint Ganna; Rak-Raszewska Aleksandra; Vainio Seppo J.

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Kidney development and perspectives for organ engineering

机译：器官工程的肾脏发展与透视

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Organ transplantation is currently the best strategy for treating end stage renal disease (ESRD) but the numbers of donor kidneys available are not sufficient to meet the needs of the ever-increasing ESRD population. Therefore, developments in the field of tissue engineering are necessary to provide alternative treatments. Decellularization and three-dimensional (3D) bioprinting strategies may serve as attractive novel options. Since successful tissue engineering requires an in -depth understanding of organ development and regulatory pathways, we discuss signaling in renal development and the composition of the renal extracellular matrix before presenting progress in the decellularization and 3D bioprinting fields.

机译：器官移植目前是治疗末期肾病（ESRD）的最佳策略，但可用的供体肾脏的数量不足以满足不断增加的ESRD人群的需求。因此，需要在组织工程领域的发展提供替代治疗。脱细胞化和三维（3D）生物监测策略可以作为有吸引力的小说选择。由于成功的组织工程需要在对器官发展和监管途径的理解中，我们讨论了肾脏发展中的信号传导和肾细胞外基质的组成，然后在脱细胞化和3D生物印刷场进展之前。

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来源
《Cell and Tissue Research》 |2017年第1期|共13页
作者
Reint Ganna; Rak-Raszewska Aleksandra; Vainio Seppo J.;
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作者单位

Bioctr Oulu Lab Dev Biol FIN-90014 Oulu Finland;

Bioctr Oulu Lab Dev Biol FIN-90014 Oulu Finland;

Bioctr Oulu Lab Dev Biol FIN-90014 Oulu Finland;

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正文语种 eng
中图分类细胞生物学;
关键词
Kidney development; Extracellular matrix; Decellularization; 3D bioprinting;

机译：肾发育;细胞外基质;脱细胞化;3D BioPlinting;

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1. Kidney development and perspectives for organ engineering [J] . Reint Ganna, Rak-Raszewska Aleksandra, Vainio Seppo J. Cell and Tissue Research . 2017,第1期

机译：器官工程的肾发展与透视
2. Constructing kidney-like tissues from cells based on programs for organ development: toward a method of in vitro tissue engineering of the kidney. [J] . Rosines E, Johkura K, Zhang X, Tissue engineering, Part A . 2010,第8期

机译：根据器官发育程序从细胞构建肾样组织：一种肾脏体外组织工程方法。
3. Constructing kidney-like tissues from cells based on programs for organ development: toward a method of in vitro tissue engineering of the kidney. [J] . Rosines E, Johkura K, Zhang X, Tissue engineering, Part A . 2010,第8期

机译：基于器官发展方案构建来自细胞的肾脏类组织：朝着肾脏体外组织工程的方法。
4. Kidney Regeneration Using Stem Cells And Acellular Whole Organ Scaffolds:Perspective And Recent Developments [C] . Edward A. Ross World congress on medical physics and biomedical engineering;International congress of the IUPESM . 2011

机译：使用干细胞和无细胞全器官支架进行肾脏再生：展望与最新发展
5. Kidney tissue engineering using decellularized organs and pluripotent stem cells. [D] . Williams, Matthew James. 2013

机译：使用脱细胞器官和多能干细胞进行肾脏组织工程。
6. Constructing Kidney-like Tissues from Cells Based on Programs for Organ Development: Toward a Method of In Vitro Tissue Engineering of the Kidney [O] . Eran Rosines, Kohei Johkura, Xing Zhang, -1

机译：基于器官发育程序从细胞构建肾样组织：肾脏的体外组织工程方法
7. Constructing Kidney-like Tissues from Cells Based on Programs for Organ Development: Toward a Method of In Vitro Tissue Engineering of the Kidney [O] . Rosines, Eran, Johkura, Kohei, Zhang, Xing, 2010

机译：基于器官发育程序从细胞构建肾样组织：肾脏的体外组织工程方法

Kidney development and perspectives for organ engineering

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