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Aging and the treatment of basal cell carcinoma

机译：老化和基础细胞癌的治疗

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Basal cell carcinoma (BCC) is the most commonly diagnosed type of skin cancer. BCCs are especially prevalent in the elderly population, given their association with cumulative sun exposure and other risk factors. In this contribution, we outline geriatric concepts related to the care of older adults with BCCs. We describe how a patient's life expectancy can be estimated and combined with tumor characteristics to determine lag time to benefit, a concept to better understand whether patients will experience the efficacy of a treatment within their life span. We also review the possibility of current BCC overdiagnosis and summarize the effectiveness, benefits, and risks of common treatments for BCCs, noting that all treatment modalities have special considerations when administered to older adults. hi particular, nonsurgical treatments might be preferable for older adults with a limited life expectancy. Ultimately, we argue that the decision of whether and how to treat a BCC should be the result of shared decision-making between the provider and the patient and take into account not only tumor characteristics, but also patient values and preferences. (C) 2019 Published by Elsevier Inc.
机译：基底细胞癌（BCC）是最常见的皮肤癌类型。鉴于他们与累积阳光暴露和其他风险因素的关联，BCC在老年人的群体中特别普遍。在这一贡献中，我们概述了与BCCS的老年人关心相关的老年人概念。我们描述了如何估计患者的预期寿命和结合肿瘤特征来确定滞后时间，以便更好地了解患者是否会在其寿命中遇到治疗的疗效。我们还审查了现有的BCC过度诊断的可能性，并总结了BCCS常见治疗的有效性，益处和风险，并指出所有治疗方式在给老年人施用时都有特殊考虑因素。特别是，对于寿命有限的老年人，可能对非诊断治疗可能是优选的。最终，我们争辩说是否以及如何对待BCC的决定应该是提供者和患者之间共享决策的结果，并不仅考虑肿瘤特征，还考虑患者的价值和偏好。 （c）2019由elsevier公司出版

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