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Strategies for optimizing medication adherence in schizophrenia

机译:优化精神分裂症中药物粘附的策略

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Medication nonadherence is a common problem in the treatment of schizophrenia. The consequences of nonadherence are numerous and can be quite serious, including increased risk of rehospitalization and suicide. There are numerous factors that affect a patient's decision and ability to take medication, including medication efficacy and tolerability, treatment regimen, cognitive deficits, and the patient's relationship with the treatment team. Fortunately, there are several strategies that may increase treatment adherence, including individualization of medication selection and dosing strategy to maximize efficacy and minimize adverse side effects, utilization of long-acting injectable depot formulations that eliminate the need for the patient to remember daily oral medication, and psychosocial approaches that emphasize the benefits of staying well.
机译:药物不正常是治疗精神分裂症的常见问题。 非正畸的后果众多,并且可能是非常严重的,包括增加再生的风险和自杀。 有许多因素影响患者的决定和服用药物的能力,包括药物疗效和耐受性,治疗方案,认知缺陷以及与治疗团队的关系。 幸运的是,有几种策略可能会增加治疗依从性,包括药物选择和给药策略的个体化,以最大限度地提高疗效,并最大限度地减少不良副作用,利用长效可注射仓库制剂,消除患者需要记住每日口服药物的需求, 和精神病的方法强调保持良好的好处。

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