Second generation antihistamines: an update

Mario Sanchez-Borges; Ignacio J. Ansotegui

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Second generation antihistamines: an update

机译：第二代抗组胺药：更新

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Purpose of review This article presents an update on the clinical pharmacology, mechanisms of action, and safety of second generation antihistamines (SGAHs). Recent findings Recent research has shown the efficacy and good tolerance of SGAHs supporting its indication as first line medications for the treatment of allergic rhinoconjunctivitis and urticaria. Summary The information contained in this review is relevant for the correct utilization of SGAHs by practicing physicians who take care of these highly prevalent clinical disorders.

机译：审查目的本文提出了关于临床药理学，行动机制和第二代抗组胺药（SGAH）的安全性的更新。最近的研究结果最近的研究表明，SGAHS支持其指示作为治疗过敏性鼻咽炎和荨麻疹的第一线药物的疗效和良好耐受性。发明内容本综述中所载的信息与练习照顾这些高度普遍临床疾病的医生正确使用SGAH。

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《Current opinion in allergy and clinical immunology》 |2019年第4期|共7页
作者
Mario Sanchez-Borges; Ignacio J. Ansotegui;
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作者单位

Allergy and Clinical Immunology Department Centra Medico Docente La Trinidad and Clinica El Avila;

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原文格式 PDF
正文语种 eng
中图分类医学免疫学;
关键词
allergic rhinitis; angioedema; antihistamines; urticaria;

机译：过敏性鼻炎;血管血清;抗组胺药;荨麻疹;

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1. CSACI position statement: Newer generation H 1 -antihistamines are safer than first-generation H 1 -antihistamines and should be the first-line antihistamines for the treatment of allergic rhinitis and urticaria [J] . Michael N. Fein, David A. Fischer, Andrew W. O’Keefe, Allergy, Asthma & Clinical Immunology . 2019,第1期

机译：CSACI立场声明：新一代H 1-抗组胺药比第一代H 1-抗组胺药更安全，应成为治疗变应性鼻炎和荨麻疹的一线抗组胺药
2. Safety of antihistamines in children: Need for approval of new second-generation antihistamines for young children in Japan [J] . ShimojoN. Clinical & experimental allergy reviews . 2012,第1期

机译：儿童抗组胺药的安全性：日本需要批准新型的第二代抗组胺药
3. Antihistaminic, Anti-Inflammatory, and Antiallergic Properties of the Nonsedating Second-Generation Antihistamine Desloratadine: a Review of the Evidence [J] . G Walter Canonica, Michael Blaiss World Allergy Organization Journal . 2011,第2期

机译：非镇静性第二代抗组胺药去氯雷他定的抗组胺，抗炎和抗过敏特性：证据综述
4. LAS 36674, A New Generation of H1 Antihistamines: From Bench to Bedside and Back [C] . M. Miralpeix, X. Cabarrocas, A. Cardenas, Collegium Internationale Allergologicum . 2007

机译：LAS 36674，新一代H1抗组胺药：从长凳到床边和背部
5. The second-generation sensitivity-based element-by-element method for updating dynamic finite element models. [D] . Brown, Gregory Wayne. 1999

机译：第二代基于灵敏度的逐要素更新动态有限元模型的方法。
6. CSACI position statement: Newer generation H1-antihistamines are safer than first-generation H1-antihistamines and should be the first-line antihistamines for the treatment of allergic rhinitis and urticaria [O] . Michael N. Fein, David A. Fischer, Andrew W. O’Keefe, 2019

机译：CSACI立场声明：新一代H1抗组胺药比第一代H1抗组胺药更安全应成为治疗变应性鼻炎和荨麻疹的一线抗组胺药
7. CSACI position statement: Newer generation H1-antihistamines are safer than first-generation H1-antihistamines and should be the first-line antihistamines for the treatment of allergic rhinitis and urticaria [O] . Michael N. Fein, David A. Fischer, Andrew W. O’Keefe, 2019

机译：CSACI位置陈述：较新一代H1-抗组胺药比第一代H1-抗组胺素更安全，应该是治疗过敏性鼻炎和荨麻疹的一线抗组胺药
8. First-Generation H1 Antihistamines Found in Pilot Fatalities of Civil Aviation Accidents, 1990-2005 [R] . Sen, A. , Akin, A. , Craft, K. J. , 2007

机译：第一代H1抗组胺药在1990 - 2005年民航事故死亡人数中发现

Second generation antihistamines: an update

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