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Treatment of the patient with achalasia

机译:用贲门刺患者治疗患者

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Purpose of review: In recent years, several studies on the treatment and follow-up of achalasia have been published. This review aims at highlighting interesting publications from the recent years. Recent findings: Treatment of achalasia aims at relieving functional obstruction at the level of the esophagogastric junction. Several treatment options such as pneumodilation and laparoscopic Heller myotomy (LHM) are available for this purpose. A large prospective randomized trial comparing pneumodilation and LHM demonstrated comparable success rates and quality of life for the two treatment options. Long-term data demonstrate comparable treatment success rates, when redilation in case of recurrent symptoms after pneumodilation is accepted. The most important risk factor for treatment failure is the manometric subtype, with a worse outcome for type I and type III compared with type II achalasia. Recently, peroral endoscopic myotomy (POEM) has been described with high success rates. Comparative studies with longer follow-up are awaited. A prospective study assessing the risk of esophageal carcinoma in patients with achalasia showed a 28-fold increased risk to develop carcinoma. Summary: Either LHM or pneumodilation have high comparable short-term clinical success rates. Based on the increased risk to develop esophageal carcinoma, a screening program may be indicated. POEM is a new interesting treatment but longer follow-up data are awaited.
机译:审查目的:近年来,有几项关于贲门划分的治疗和后续行动的研究已发表。该评论旨在突出近年来突出有趣的出版物。最近的发现:贲门划分的治疗旨在缓解食管胃部级别的功能障碍。若干治疗方案如肺炎和腹腔镜Heller Myotomy(LHM)可用于此目的。对比较肺炎和LHM的大型前瞻性随机试验表明了两种治疗方案的可比成功率和生活质量。长期数据表明了可比的治疗成功率,当接受肺炎后经常发生的症状时冗余。治疗失败的最重要的危险因素是粪便亚型,与II型贲门累染症相比,I型和III型更差的结果。最近,已经用高成功率描述了情化内窥镜肌动术(诗)。等待更长时间的比较研究即将到来。评估贲门刺患者食管癌风险的前瞻性研究表明,发育癌的风险增加28倍。发明内容:LHM或肺炎含量高的可比性短期临床成功率。基于发育食管癌的风险增加,可以指出筛选计划。诗是一种新的有趣的治疗,但等待了更长的后续数据。

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