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Incidental Aortic Valve Calcification on CT Scans. Significance for Bicuspid and Tricuspid Valve Disease

机译:CT扫描的偶然主动脉瓣钙化。 双裂和三尖瓣病的意义

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摘要

Rationale and Objectives: The aim of this study was to evaluate the role of incidental aortic valve calcification on routine computed tomographic scans as a marker for stenosis, as assessed by echocardiography, in patients with bicuspid aortic valve (BAV) and tricuspid aortic valve. Materials and Methods: Computed tomographic and echocardiographic studies were retrospectively reviewed for 182 consecutive, unselected patients and 426 patients identified by a record search for "aortic valve calcification." Location and severity of valve calcification were correlated with aortic valve morphology and stenosis. Differences between subgroups were assessed using χ 2 or Fisher's exact tests. Results: In unselected patients, calcification was present in 25.8% with tricuspid aortic valves (46 of 178) and 75% (three of four) with BAV. In patients selected for valve calcification, the average age of those with tricuspid aortic valves (n = 395) was 14.3 years older than those with BAV (n = 31). Patients with BAV were more likely to have severe calcification (87% vs 50%, P .001), and if severe calcification was present, it was more likely to involve only the valve leaflets (41% vs 9%, P .001) and result in aortic stenosis (85% vs 58%, P = .006). Patients aged 60 years with severe calcification were more likely to have BAV (56% vs 7%; odds ratio, 7.9; 95% confidence interval, 3.4-18.7). Conclusions: Aortic valve calcification was found 14 years earlier in patients with BAV and was more severe and strongly linked to aortic stenosis. Valve calcification on computed tomographic scans should be considered a marker for BAV if found before the seventh decade.
机译:理由和目标:本研究的目的是评估偶然主动脉瓣钙化对常规计算断层扫描作为狭窄的标志物的作用,如超声心动图评估的双囊主动脉瓣(BAV)和三尖瓣主动脉瓣。材料和方法:通过记录搜索“主动脉瓣钙化”的连续,未选择的患者和426名患者,回顾性地审查了计算断层和超声心动图研究。阀门钙化的位置和严重程度与主动脉瓣膜形态和狭窄相关。使用χ2或费舍尔的确切测试评估子组之间的差异。结果:在未选择的患者中,钙化以25.8%的钙化,Tricuspid主动脉瓣(178个)和75%(三种)与BAV。在选择阀门钙化的患者中,三尖瓣主动脉瓣(n = 395)的平均年龄比BAV(n = 31)大14.3岁。 BAV患者更容易具有严重钙化(87%Vs 50%,P& .001),并且如果存在严重钙化,则更有可能涉及瓣膜小叶(41%Vs 9%,P&LT ;001)并导致主动脉狭窄(85%Vs 58%,p = .006)。患者衰减严重钙化的60年更有可能拥有BAV(56%vs 7%;赔率比,7.9; 95%置信区间,3.4-18.7)。结论:BAV患者14年来发现主动脉瓣钙化,并更严重,与主动脉狭窄相关。如果在第七十年之前发现,那么计算机扫描对计算机断层扫描的钙化应被视为BAV的标志。

著录项

  • 来源
    《Academic radiology》 |2012年第5期|共6页
  • 作者单位

    Department of Radiology University of California San Francisco 505 Parnassus Avenue Box 0628;

    Department of Radiology University of California San Francisco 505 Parnassus Avenue Box 0628;

    Department of Radiology University of California San Francisco 505 Parnassus Avenue Box 0628;

    Department of Cardiothoracic Surgery San Francisco Veterans Affairs Medical Center San Francisco;

    Department of Cardiothoracic Surgery San Francisco Veterans Affairs Medical Center San Francisco;

  • 收录信息
  • 原文格式 PDF
  • 正文语种 eng
  • 中图分类 放射医学;
  • 关键词

    Aortic stenosis; Aortic valve calcification; Bicuspid aortic valve;

    机译:主动脉狭窄;主动脉瓣钙化;双裂主动脉瓣;

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