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首页> 外文期刊>Academic radiology >Comparison of Aortic Arch and Intravenous Contrast Injection Techniques for C-arm Cone Beam CT. Implications for Cerebral Perfusion Imaging in the Angiography Suite.
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Comparison of Aortic Arch and Intravenous Contrast Injection Techniques for C-arm Cone Beam CT. Implications for Cerebral Perfusion Imaging in the Angiography Suite.

机译：基于C形臂锥梁CT的主动脉弓和静脉内对比注射技术的比较。 对血管造影套房脑灌注成像的影响。

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Rationale and Objectives: The ability to perform cerebral perfusion imaging (CPI) in the angiography suite has provided a new tool for diagnosis and treatment of neurovascular patients but requires comparable contrast perfusion to each cerebral hemisphere. In the angiography suite, contrast injection may be performed via an intra-arterial or intravenous (IV) route. The purpose of this study was to investigate whether a difference exists between contrast injection in the aortic arch (AA) and a peripheral vein (IV), particularly in the setting of stroke. Materials and Methods: Using three canines, both AA and IV injection protocols compatible with CPI were performed prospectively at three time points after creation of a stroke. The common carotid arteries in the resulting image data sets were segmented and the means and distributions of corresponding pixel intensities analyzed with Student's t-test. Using similar techniques, the internal carotid arteries of three patients (one female, two males, ages 69, 29, and 20) undergoing AA contrast injection with cone beam computed tomography (CBCT) cerebral imaging were analyzed and compared retrospectively with those of three random patients (one female, two males, ages 19, 57, and 35) undergoing standard head CT scans using IV contrast administration. All acquisitions followed institutionally approved protocols and informed consent. Results: No statistical significance (P <.05) was found when mean values for the right and left carotid artery pixel intensities were compared in the canine model or the clinical studies in which patients underwent imaging after AA or IV contrast administration. Conclusions: No statistically significant difference exists between right and left carotid artery filling density using either AA or IV contrast injection methods, making both suitable for CPI in the angiography suite.
机译：理由和目标：在血管造影套房中进行脑灌注成像（CPI）的能力为神经血管患者的诊断和治疗提供了新的工具，但需要对每个脑半球进行相当的对比度灌注。在血管造影套件中，可以通过动脉内或静脉内（IV）途径进行对比度注射。本研究的目的是探讨在主动脉弓（AA）和外周静脉（IV）中的对比注射之间是否存在差异，特别是在卒中的设置中。材料和方法：使用三个犬物，在创建行程后，在三个时间点前瞻性地进行与CPI相容的AA和IV注射方案。将结果图像数据集中的常见颈动脉进行分段，并在学生的T检验中分析了相应的像素强度的装置和分布。使用类似的技术，分析了与锥梁计算断层扫描（CBCT）脑成像进行了对锥形射击的AA对比注射（CBCT）脑成像的三个患者的内部颈动脉（一种雌性，两名男性，69,29,29,29和20岁），并回顾性与三个随机的那些使用IV对比度给药，患者（一名女性，两名男性，25岁，19,57和35岁，35岁）进行标准头CT扫描。所有收购遵循机构批准的议定书和知情同意书。结果：在犬模型中比较右颈和左颈动脉像素强度的平均值或临床研究中没有发现统计学意义（P <.05）。结论：使用AA或IV对照注射方法，右侧颈动脉填充密度不存在统计学上显着差异，适用于血管造影套件中的CPI。

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