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首页> 外文期刊>AIDS care. >Alcohol-related intentional nonadherence to antiretroviral therapy among people living with HIV, Cape Town, South Africa
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Alcohol-related intentional nonadherence to antiretroviral therapy among people living with HIV, Cape Town, South Africa

机译：与艾滋病毒，开普敦，南非居民主义抗逆转录病毒治疗的酒精相关的故意抗逆病毒治疗

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Alcohol use may have significant negative impacts on individuals' ability to remain adherent to antiretroviral therapy (ART), and may also yield other negative psychosocial, health-related, and behavioral outcomes. In addition, false beliefs about the consequences of mixing alcohol with ART use may cause individuals to avoid taking ART when drinking (alcohol-related ART avoidance). Although research conducted in the U.S. and Europe has reported on alcohol-ART avoidance, the current study presents among the first quantitative evidence of alcohol-related intentional ART nonadherence in South Africa. Patients receiving ART from a community clinic in Cape Town (N = 441) completed anonymous surveys of alcohol use, ART adherence, and alcohol-ART avoidance. Results showed that 292 (66%) participants reported current alcohol use; 25% who use alcohol believed that people who drink should stop taking ART when they are drinking and 24% stop their own ART when drinking. Alcohol-ART avoidance mediated the association between alcohol use and ART adherence. Results were robust when controlling for participant age, gender, current care status, and first- versus second-line ART. We found alcohol-ART avoidance may threaten successful ART in South Africa. Corrective messages that take a harm reduction approach to maximize ART adherence when drinking should be implemented in existing clinical services.
机译：酒精使用可能对个体保留抗逆转录病毒治疗（ART）的能力产生显着的负面影响，也可能产生其他负面的心理社会，与健康有关和行为结果。此外，关于用艺术用途混合酒精的后果的错误信念可能会使个体避免饮用时（饮酒有关的艺术避免）。虽然在美国和欧洲进行了研究，但在南非酗酒的有意艺术不正常的第一次定量证据中，目前的研究表现出了目前的研究。从开普敦（N = 441）的社区诊所接受艺术的患者完成了匿名调查的酒精使用，艺术遵守和饮料避免。结果表明，292（66％）参与者报告了当前的酒精使用; 25％的人使用酒精相信喝酒应该在喝酒时停止艺术，而24％在喝酒时停止自己的艺术。饮酒避免介导酒精使用和艺术粘附之间的关联。结果在控制参与者年龄，性别，当前护理地位和第一款二线艺术品时具有强大。我们发现酒精艺术避免可能会在南非威胁成功的艺术。应在现有的临床服务中实施纠正措施以最大限度地提高艺术遵守的措施，以最大限度地实现艺术依从性。

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