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首页> 外文期刊>Analytical methods >A rapid and highly selective paper-based device for high-throughput detection of cysteine with red fluorescence emission and a large Stokes shift
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A rapid and highly selective paper-based device for high-throughput detection of cysteine with red fluorescence emission and a large Stokes shift

机译：一种快速且高度选择性的纸质装置，用于荧光发射红色荧光发射的半胱氨酸和大型斯托克斯的高通量检测

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摘要

A paper-based device is a promising technology for point-of-care testing (POCT). In this work, a novel fluorescent probe with red emission (650 nm) and a large Stokes shift (similar to 170 nm) for Cys detection was reported for the first time. This probe exhibited a highly selective and rapid response to Cys within 5 min. Importantly, by introducing this probe into microfluidic paper-based analytical devices (mPADs), a paper-based device was developed for simple, high-throughput and highly sensitive detection of Cys. Finally, satisfactory performance of this paper-based device for Cys detection was achieved in real samples, which indicates the great potential of our strategy in the construction of POCT systems for detecting analytes.
机译：基于纸张的设备是一种有希望的技术，可用于护理点测试（POCT）。 在这项工作中，首次报告了一种具有红色发射（650nm）的新型荧光探针和用于Cys检测的大型Stokes偏移（类似于170nm）。 该探头在5分钟内表现出对Cys的高度选择性和快速反应。 重要的是，通过将该探针引入基于微流体纸张的分析装置（MPADS），开发了一种基于纸张的装置，用于简单，高通量和对Cys的高敏感性检测。 最后，在真正的样本中实现了这种基于纸张的Cys检测装置的令人满意的性能，这表明我们在策略施工中检测分析物的策略的巨大潜力。

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  • 来源
    《Analytical methods》 |2019年第10期|共5页
  • 作者

    Zhou Jia; Yu Changmin; Li Zheng; Peng Pingping; Zhang Duoteng; Han Xun; Tang Hezhou; Wu Qiong; Li Lin; Huang Wei;

  • 作者单位

    Nanjing Tech Univ NanjingTech KLOFE Jiangsu Natl Synerget Innovat Ctr Adv Mat SICAM 30 South Puzhu Rd Nanjing 211816 Jiangsu Peoples R China;

    Nanjing Tech Univ NanjingTech KLOFE Jiangsu Natl Synerget Innovat Ctr Adv Mat SICAM 30 South Puzhu Rd Nanjing 211816 Jiangsu Peoples R China;

    Nanjing Tech Univ NanjingTech KLOFE Jiangsu Natl Synerget Innovat Ctr Adv Mat SICAM 30 South Puzhu Rd Nanjing 211816 Jiangsu Peoples R China;

    Nanjing Tech Univ NanjingTech KLOFE Jiangsu Natl Synerget Innovat Ctr Adv Mat SICAM 30 South Puzhu Rd Nanjing 211816 Jiangsu Peoples R China;

    Nanjing Tech Univ NanjingTech KLOFE Jiangsu Natl Synerget Innovat Ctr Adv Mat SICAM 30 South Puzhu Rd Nanjing 211816 Jiangsu Peoples R China;

    NPU SIFE 127 West Youyi Rd Xian 710072 Shaanxi Peoples R China;

    NPU SIFE 127 West Youyi Rd Xian 710072 Shaanxi Peoples R China;

    Nanjing Tech Univ NanjingTech KLOFE Jiangsu Natl Synerget Innovat Ctr Adv Mat SICAM 30 South Puzhu Rd Nanjing 211816 Jiangsu Peoples R China;

    Nanjing Tech Univ NanjingTech KLOFE Jiangsu Natl Synerget Innovat Ctr Adv Mat SICAM 30 South Puzhu Rd Nanjing 211816 Jiangsu Peoples R China;

    Nanjing Tech Univ NanjingTech KLOFE Jiangsu Natl Synerget Innovat Ctr Adv Mat SICAM 30 South Puzhu Rd Nanjing 211816 Jiangsu Peoples R China;

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  • 原文格式 PDF
  • 正文语种 eng
  • 中图分类 分析化学;
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