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首页> 外文期刊>Annals of the Royal College of Surgeons of England >Gastric schwannoma: a benign tumour often mistaken clinically, radiologically and histopathologically for a gastrointestinal stromal tumour - a case series.
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Gastric schwannoma: a benign tumour often mistaken clinically, radiologically and histopathologically for a gastrointestinal stromal tumour - a case series.

机译:胃施瓦马诺瘤:良性肿瘤常常术语,放射学和组织病理学术语术语,用于胃肠道间质瘤 - 一个壳体系列。

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摘要

Gastric schwannomas are rare mesenchymal tumours that arise from the nerve plexus of the gut wall. They present with non-specific symptoms and are often detected incidentally. Pre-operative investigation is not pathognomonic and many are therefore diagnosed as gastrointestinal stromal tumours (GISTs). Operative resection is usually curative as they are almost always benign, underpinning the importance of differentiating them from GISTs.Three cases of gastric schwannomas were identified over a seven-year period. The clinical details and management were reviewed retrospectively.There were two women and one man with a mean age of 62 years (range: 51-69 years). Two patients presented with bleeding and one with abdominal pain. The mean tumour size was 5.2cm (range: 2-10cm) and the tumours were resected completely following total or wedge gastrectomies. Histology in all cases showed spindle cells with a cuff of lymphoid tissue. Immunohistochemistry confirmed positive S100 staining and negative CD117 and DOG-1 staining in all cases.We report our experience with these unusual primary stromal tumours of the gut and their presentations, pre-operative investigations, operative findings and pathological findings are discussed. Operative resection in all cases has been considered curative, which is supported by previous series confirming the excellent prognosis of gastric schwannomas.
机译:胃施瓦莫玛是肠道神经丛的罕见间充质肿瘤。它们存在非特异性症状,并且通常偶然检测到。术前调查不是路障,因此许多被诊断为胃肠间质量肿瘤(GIST)。手术切除通常是治愈性,因为它们几乎总是良性,支撑鉴定它们的重要性,将它们与患者区分开来。在七年期间确定了胃施华瘤的三年案件。回顾性审查了临床细节和管理。有两名妇女和一个男子,平均年龄为62岁(范围:51-69岁)。两名患者患有出血和腹痛。平均肿瘤大小为5.2cm(范围:2-10厘米),并完全伴随总或楔形胃切除术后切除肿瘤。在所有情况下组织学显示用淋巴组织的袖带显示主轴细胞。免疫组织化学证实了阳性S100染色和阴性CD117和所有情况下的狗-1染色。我们向肠道的这些异常的初级基质肿瘤报告了我们的演示文稿,术前调查,手术结果和病理学发现。所有病例的手术切除已被认为是治愈性的,其通过之前的系列提供支持,证实了胃施瓦莫纳斯的优异预后。

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