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首页> 外文期刊>Indian journal of physiology and pharmacology >Visual Evoked Potential in Megaloblastic Anemia : A Cross Sectional Study
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Visual Evoked Potential in Megaloblastic Anemia : A Cross Sectional Study

机译：巨大的贫血中的视觉诱发潜力：横截面研究

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Megaloblastic anemia is the second mostcommon type of anemia after iron deficiencyanemia. Itresults from faulty DNA synthesis attributed to vitamin B12 or folic acid deficiency & may be associated with neuropathy which can lead to substantial morbidity if unrecognized or misdiagnosed.The aim of the study was to evaluate the Visual evoked potential (VEP) in megaloblastic anemia. VEP provide a non-invasive method of assessingneurological function. A delayed VEP supports the diagnosis of optic neuropathy.The study was conducted in 100 subjects- 50 controls and 50 patients of megaloblastic anemia diagnosed by low haemoglobin levels along with increased MCV, low serum vitamin B12 or bone marrow changes or both. Patients were tested for visual acuity, field of vision and colour vision. Pattern reversal VEP was carried out. P100 latency and amplitude were measured.VEP revealed prolongation of P100 latency when compared with control group which was statistically significant. VEP can be used as an early indicator of optic nerve involvement in patients with asymptomatic megaloblastic anemia.
机译：MegaloBolastic贫血是铁病毒血症后的第二种最常见的贫血。来自归因于维生素B12或叶酸缺乏的故障DNA合成的ITResults可能与神经病变有关，如果未被识别或误诊，可以导致大量发病率。该研究的目的是评估巨大的患有巨大血症的视觉诱发潜力（VEP）。 VEP提供了评估的非侵入性方法。延迟的VEP支持视神经病变的诊断。该研究是在100个受试者 - 50个对照组中进行的，并通过低血红蛋白水平诊断出的50例对照组和50例患有低血红蛋白水平的患者，以及增加的MCV，低血清维生素B12或骨髓变化或两者。测试患者的视力，视野和颜色视野。进行模式逆转Vep进行。测量P100潜伏和振幅。与统计学意义的对照组相比，载体显示了P100潜伏期的延长。 VEP可以用作无症状患者患者的视神经受患者的早期指标。

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