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首页> 外文期刊>International journal of colorectal disease. >Colorectal carcinoma in different age groups: A histopathological analysis
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Colorectal carcinoma in different age groups: A histopathological analysis

机译：不同年龄组的结肠直肠癌：组织病理学分析

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Purpose Although colorectal cancer is typical in the older population, tumor onset before age 40 is not infrequent. However, the behavior, characteristics, and prognosis of this disease in young patients are unclear when compared to the older population. It is believed that young patients have apoor prognosis. We hypothesized that young patients have apoor prognosis because they have advanced-stage cancer with more aggressive pathologic features. Methods Using a university hospital database, we analyzed the histopathological features of three groups of patients with a diagnosis of colorectal cancer: young age group (patients 40 years and younger), intermediate age group (patients 41-80 years old), and old age group (patients 81 years and older). Results A total of 653 cases of colorectal cancer were analyzed. The young age group comprised 48 patients (7.4%), the intermediate age group comprised 538 patients (82.4%) and the old age group consisted of 67 patients (10.3%).The gender distribution was similar between the groups. The mean age of the young, intermediate, and old age groups were 34.5 (plusmn;5.0), 61.7 (plusmn;11.1) and 85.1 (plusmn;4.6) years old, respectively. The pathological features analyzed such as lymph node involvement, tumor histological classification and grade, venous, neural and lymphatic invasion, T and N classification of the TNM System, and Astler-Coller classification were similar between the age groups. Conclusions The colorectal histopathological features in young patients are similar to older patients. More aggressive characteristics or more advanced stage are not seen in younger patients.
机译：目的虽然年龄较大的癌症典型的癌症典型，但在40岁之前的肿瘤发作并不少。然而，与年龄较大的人群相比，年轻患者这种疾病的行为，特征和预后尚不清楚。据信，年轻的患者具有Apoor预后。我们假设年轻患者具有Apoor预后，因为它们具有高级阶段的癌症，具有更具侵略性的病理特征。方法采用大学医院数据库，分析了三组患者的结直肠癌诊断的组织病理学特征：年龄组（患者40岁），中等年龄组（患者41-80岁），老年龄组（患者81岁及以上）。结果分析了总共653例结直肠癌。年龄组组成48名患者（7.4％），中等年龄组包含538名患者（82.4％），年龄组由67名患者组成（10.3％）。群体之间的性别分布类似。年轻，中级和旧年龄组的平均年龄为34.5（PLUSMN; 5.0），61.7（PLUSMN; 11.1）和85.1（PLUSMN; 4.6）岁。分析的病理特征如淋巴结受累，肿瘤组织学分类和等级，静脉，神经和淋巴侵蚀，T和N分类，年龄组之间的哮员分类和astler-coller分类。结论年轻患者的结肠直肠组织病理学特征与老年患者相似。在较年轻的患者中没有看到更具侵略性的特征或更高阶段。

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