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首页> 外文期刊>International journal of rheumatic diseases >Active synovitis in the presence of osteitis predicts residual synovitis in patients with rheumatoid arthritis with a clinical response to treatment
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Active synovitis in the presence of osteitis predicts residual synovitis in patients with rheumatoid arthritis with a clinical response to treatment

机译：在骨炎存在下的活性滑膜炎预测类风湿性关节炎患者残留的滑膜炎，临床反应治疗

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Abstract Aim To clarify the relationship between active synovitis/osteitis and subsequent residual synovitis (R‐synovitis) in patients with rheumatoid arthritis ( RA ). Methods Three hundred and twenty finger joints of 16 patients with active RA at baseline (Disease Activity Score with 28 joints – erythrocyte sedimentation rate 3.2) who subsequently achieved clinical low disease activity or remission afterwards were analyzed. Synovial vascularity ( SV ) was assessed according to a semi‐quantitative ultrasound score (grades 0–3). Active synovitis was defined by SV positivity at baseline. R‐synovitis was defined by the presence of grade 2 SV at the 24th week. Osteitis was detected by magnetic resonance imaging ( MRI ) at baseline as trabecular bone lesions with water content and indistinct margins. Results Ultrasonography detected active synovitis in 116 joints at baseline. Forty‐seven joints had R‐synovitis at the 24th week. MRI detected osteitis in 12 joints at baseline. The presence of active synovitis with osteitis at baseline was significantly correlated with R‐synovitis at the 24th week. Conclusions Active synovitis in the presence of osteitis predicted R‐synovitis regardless of whether there was a clinical improvement in RA .
机译：摘要旨在阐明类风湿性关节炎（RA）患者中活性滑膜炎/骨炎和随后残留滑膜炎（R-滑动炎）的关系。方法对基线有效RA患者的三百和二十个手指关节（疾病活动评分，患有28个关节 - 红细胞沉降率＆ 3.2）后者后续达到临床低疾病活动或缓解。根据半定量超声评分评估滑膜血管（SV）（0-3级）。活性滑膜炎通过基线的SV阳性定义。 R-滑膜炎由等级和gt的存在定义; 24周的2 SV。磁共振成像（MRI）在基线下检测骨炎，如带有水含量和模糊边缘的小梁骨病变。结果超声检查检测到基线116个关节中的活性滑膜炎。第四十七个关节在第24周具有R-滑膜炎。 MRI在基线中检测到12个关节中的骨炎。在第24周的第24周与基线上具有骨炎的活性滑膜炎的存在显着相关。结论无论RA是否存在临床改善，无论RA如何，都会结论活性滑膜炎是否存在骨质炎。

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