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首页> 外文期刊>European journal of gastroenterology and hepatology >Epidemiology of hepatitis B in Portugal
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Epidemiology of hepatitis B in Portugal

机译:葡萄牙乙型肝炎的流行病学

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The epidemiology of hepatitis B in Portugal is insufficiently characterized. We aimed to review the epidemiology of hepatitis B in Portugal since 1980. A literature review was performed in MEDLINE, Scielo, Web of Science, and the Portuguese Scientific Repository for studies containing 'Hepatitis B' and 'Portugal' published from 1980 to June 2016. The initial search was complemented by abstract books from national gastroenterology and hepatology meetings and reports from the Service for Intervention on Addictive Behaviours and Dependences, the Portuguese Blood Institute, and Directorate-General of Health. Further studies were identified in references of retrieved papers and https://www.google.pt. Ninety references were included. Hepatitis B surface antigen (HBsAg) prevalence was up to 2% in the general population and decreased in the last decades: 1.13-2.0% in studies carried out in 1980-1989 and 0.02-1.45% in studies carried out in 1990-2014. Among pregnant women, HBsAg prevalence was 1.35% in those on primary care, but 6.2% among risk parturients. Among drug abusers, HBsAg prevalence decreased from 10-19.6% in the decades of 1980-1990 to 4.8% in 2014. Higher HBsAg prevalence rates were observed among populations of African or Asian origin. Individuals with hepatitis B were mostly men, mean age 36.9-49 years. The most frequent viral genotype was D. Genotype E is more prevalent in patient cohorts from Central-Southern Portugal (10-62%) than those from Northern Portugal (1-4.1%). The proportion of inactive carriers varied from 24.2 to 73%. The prevalence of cirrhosis varied from 5.8 to 23.7%. Portugal is a low-endemicity country for hepatitis B. Nevertheless, prevalence is high among specific subgroups that may benefit from specifically designed healthcare programs. Copyright (C) 2017 Wolters Kluwer Health, Inc. All rights reserved.
机译:葡萄牙乙型肝炎的流行病学表现得不足。我们旨在自1980年以来审查葡萄牙乙型肝炎的流行病学。在Medline,Scielo,科学网站和葡萄牙科学储存库中进行了文献综述,葡萄牙科学储存库含有1980年至2016年6月出版的“乙型肝炎”和“葡萄牙”的研究。初始搜索是由国家胃肠学和肝脏会议的抽象书籍补充,并从服务干预令人上瘾行为和依赖,葡萄牙血液研究所和卫生总局的服务。在检索的论文和https://www.google.pt的参考文献中鉴定了进一步的研究。包括九十参考文献。乙型肝炎表面抗原(HBsAg)普遍存在的普遍存产高达2%,在过去十年中减少:1980年至1989年的研究中进行1.13-2.0%,在1990 - 2014年进行的研究中进行了0.02-1.45%。在孕妇中,HBsAg患病率为1.35%,初级保健,但风险养殖中的6.2%。在吸毒者中,HBsAg患病率从2014年的十年减少了10-19.6%至2014年的4.8%。非洲或亚洲人口的人口中观察到更高的HBsAg患病率。乙型肝炎的个体主要是男性,平均年龄为36.9-49岁。最常见的病毒基因型是D.基因型E在葡萄牙中部(10-62%)的患者群体中比来自葡萄牙北部(1-4.1%)的患者群体更普遍。非活动载体的比例从24.2变化到73%。肝硬化的患病率不同于5.8%至23.7%。葡萄牙是乙型肝炎的低流行性国家,仍然可以从专门设计的医疗保健计划中受益的特定子组中患病率很高。版权所有(C)2017 Wolters Kluwer Health,Inc。保留所有权利。

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