Severe Asthma in Childhood

Marko Angela; Ross Kristie R.

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Severe Asthma in Childhood

机译：童年时期的严重哮喘

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Severe asthma is broadly defined as asthma requiring a high level of therapy, usually high doses of inhaled corticosteroids, to bring under control. Children who remain symptomatic despite such treatment are a heterogeneous population, and bear a high burden of disease and require high resource utilization. Children with severe asthma require a comprehensive evaluation, careful consideration of alternative diagnoses and comorbid conditions, assessment of medication adherence and environmental conditions, and frequent disease monitoring.

机译：严重的哮喘广泛地定义为需要高水平治疗的哮喘，通常是高剂量的吸入皮质类固醇，以进行控制。尽管这种治疗仍然存在症状的儿童是一种异质人群，并且具有高度疾病负担，需要高资源利用。严重哮喘的儿童需要综合评价，仔细考虑替代诊断和合并症条件，评估药物粘附和环境条件，以及频繁的疾病监测。

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来源
《Immunology and allergy clinics of North America》 |2019年第2期|共16页
作者
Marko Angela; Ross Kristie R.;
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作者单位

Univ Hosp Rainbow Babies &

Childrens Hosp Div Pediat Pulmonol 11100 Euclid Ave Cleveland OH;

Case Western Reserve Univ Univ Hosp Rainbow Babies &

Childrens Hosp Sch Med 11100 Euclid Ave;

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原文格式 PDF
正文语种 eng
中图分类医学免疫学;
关键词
Severe asthma; Children; Phenotype; Management;

机译：严重的哮喘;儿童;表型;管理;

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专利

1. Dermatophagoides in childhood asthma Allergy to dermatophagoides associates more severe childhood asthma with a potential role for acaricides [J] . Adham Tamer M., Tawfik Safwat A. Saudi medical journal. . 2012,第3期

机译：儿童哮喘中的皮肤癣菌病对皮肤癣菌的过敏将更严重的儿童哮喘与杀螨剂的潜在作用联系在一起
2. A simple tool to identify infants at high risk of mild to severe childhood asthma: The persistent Asthma predictive score [J] . VialDupuyA., AmatF., PereiraB., The journal of asthma . 2011,第10期

机译：一个简单的工具可以识别出患有轻度至重度儿童哮喘的高风险婴儿：持续的哮喘预测评分
3. Serum vitamin D levels and severe asthma exacerbations in the Childhood Asthma Management Program study. [J] . Brehm JM, Schuemann B, Fuhlbrigge AL, The Journal of Allergy and Clinical Immunology . 2010,第1期

机译：儿童哮喘管理计划研究中的血清维生素D水平和严重哮喘加重。
4. A Novel Approach to Examining Multiple Indoor Exposures in Early Childhood on the Inflammatory Pathway and Risk of Intermediate Outcomes for Childhood Asthma in the Canadian Healthy Infant Longitudinal Development (CHILD) Birth Cohort [C] . Tim K. Takaro, Martine Vrijheid, Xavier Basagana, Joint annual meeting of the International Society of Exposure Science and the International Society for Environmental Epidemiology . 2018

机译：在加拿大健康婴儿纵向发育（CHILD）队列研究中，研究了多种早期途径，研究了早期炎症途径上的多个室内暴露以及儿童哮喘中级结局的风险
5. The impact of severe housing stress on child asthma control and pediatric asthma caregiver quality of life (PACQOL). [D] . Kishore, Nina. 2014

机译：严重的住房压力对儿童哮喘控制和小儿哮喘护理人员的生活质量（PACQOL）的影响。
6. Heterogeneity of Severe Asthma in Childhood: Confirmation by Cluster Analysis of Children in the NIH/NHLBI Severe Asthma Research Program (SARP) [O] . Anne M. Fitzpatrick, W. Gerald Teague, Deborah A. Meyers, -1

机译：儿童严重哮喘的异质性：NIH / NHLBI严重哮喘研究计划中儿童的聚类分析确认（SARP）
7. Serum vitamin D levels and severe asthma exacerbations in the Childhood Asthma Management Program study [O] . John M. Brehm, Brooke Schuemann, Anne L. Fuhlbrigge, 2010

机译：血清维生素D水平和严重的哮喘恶化在儿童哮喘管理方案研究中

Severe Asthma in Childhood

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